New method of preparation of carboxy-protected amino acid conjugates of glycyrrhizinic acid
- Authors: Baltina L.A.1, Fairushina A.I.1, Baltina L.A.1
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Affiliations:
- Ufa Institute of Chemistry of the Russian Academy of Sciences
- Issue: Vol 86, No 4 (2016)
- Pages: 826-829
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/214608
- DOI: https://doi.org/10.1134/S1070363216040113
- ID: 214608
Cite item
Abstract
A method for preparation of carboxy-protected amino acid conjugates of glycyrrhizinic acid with the use of N-hydroxybenzotriazole, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide, and methyl esters of L-amino acids (phenylalanine, tyrosine, leucine, isoleucine, and methionine) in 85–90% yield was developed. The structure of the prepared compounds was confirmed by IR and 13C NMR spectra.
About the authors
L. A. Baltina
Ufa Institute of Chemistry of the Russian Academy of Sciences
Author for correspondence.
Email: baltina@anrb.ru
Russian Federation, pr. Oktyabrya 71, Ufa, 450054
A. I. Fairushina
Ufa Institute of Chemistry of the Russian Academy of Sciences
Email: baltina@anrb.ru
Russian Federation, pr. Oktyabrya 71, Ufa, 450054
L. A. Baltina
Ufa Institute of Chemistry of the Russian Academy of Sciences
Email: baltina@anrb.ru
Russian Federation, pr. Oktyabrya 71, Ufa, 450054