Email this article Synthesis and Biological Activity of Nitrilic Derivatives of the Methyl Ester of Maleopimaric Acid
- Authors: Tret’yakova E.V.1, Salimova E.V.1, Parfenova L.V.1
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Affiliations:
- Institute of Petrochemistry and Catalysis
- Issue: Vol 44, No 5 (2018)
- Pages: 547-552
- Section: Article
- URL: https://journals.rcsi.science/1068-1620/article/view/229024
- DOI: https://doi.org/10.1134/S1068162018050175
- ID: 229024
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Abstract
An effective method of a modification of the anhydride ring of the maleopimaric acid methyl ester by means of the cyanoethylation reaction was developed. A primary screening of a cytotoxic activity in vitro demonstrated an ability of the cyanoethyl derivative of the maleopimaric acid methyl ester to induce the death of the PC-3 cells of prostate cancer.
About the authors
E. V. Tret’yakova
Institute of Petrochemistry and Catalysis
Author for correspondence.
Email: tretyakovaelv@gmail.com
Russian Federation, Ufa, 450075
E. V. Salimova
Institute of Petrochemistry and Catalysis
Email: tretyakovaelv@gmail.com
Russian Federation, Ufa, 450075
L. V. Parfenova
Institute of Petrochemistry and Catalysis
Email: tretyakovaelv@gmail.com
Russian Federation, Ufa, 450075
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