Synthesis and Biological Activity of Nitrilic Derivatives of the Methyl Ester of Maleopimaric Acid
- Авторы: Tret’yakova E.V.1, Salimova E.V.1, Parfenova L.V.1
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Учреждения:
- Institute of Petrochemistry and Catalysis
- Выпуск: Том 44, № 5 (2018)
- Страницы: 547-552
- Раздел: Article
- URL: https://journals.rcsi.science/1068-1620/article/view/229024
- DOI: https://doi.org/10.1134/S1068162018050175
- ID: 229024
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Аннотация
An effective method of a modification of the anhydride ring of the maleopimaric acid methyl ester by means of the cyanoethylation reaction was developed. A primary screening of a cytotoxic activity in vitro demonstrated an ability of the cyanoethyl derivative of the maleopimaric acid methyl ester to induce the death of the PC-3 cells of prostate cancer.
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Об авторах
E. Tret’yakova
Institute of Petrochemistry and Catalysis
Автор, ответственный за переписку.
Email: tretyakovaelv@gmail.com
Россия, Ufa, 450075
E. Salimova
Institute of Petrochemistry and Catalysis
Email: tretyakovaelv@gmail.com
Россия, Ufa, 450075
L. Parfenova
Institute of Petrochemistry and Catalysis
Email: tretyakovaelv@gmail.com
Россия, Ufa, 450075
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