电邮这篇文章 Composition and properties of the reaction products of p-cresol with camphene
- 作者: Chukicheva I.1, Buravlev E.1, Dvornikova I.1, Fedorova I.1, Chernysheva G.2, Aliev O.2, Smol’yakova V.2, Anishchenko A.2, Sidekhmenova A.2, Plotnikov M.2, Kutchin A.1
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隶属关系:
- Institute of Chemistry, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
- Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center of the Russian Academy of Sciences
- 期: 卷 68, 编号 5 (2019)
- 页面: 993-999
- 栏目: Full Article
- URL: https://journals.rcsi.science/1066-5285/article/view/243370
- DOI: https://doi.org/10.1007/s11172-019-2509-0
- ID: 243370
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详细
The products of the reaction between p-cresol and camphene were isolated and characterized. Their antiradical activity and toxicity were studied. The pharmacological activity of the most active stereoisomer of 2,6-diisobornyl-4-methyl phenol in rats with a model of streptozotocin diabetes was studied. Under these conditions, the investigated compound during course administration improves micro- and macrorheological parameters of blood, exhibits a membranestabilizing eff ect on erythrocytes, restricts platelet aggregation, and favors the preservation of the vasodilator function of endothelium.
作者简介
I. Chukicheva
Institute of Chemistry, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
编辑信件的主要联系方式.
Email: chukichevaiy@mail.ru
俄罗斯联邦, 48 ul. Pervomayskaya, Syktyvkar, 167000
E. Buravlev
Institute of Chemistry, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
Email: chukichevaiy@mail.ru
俄罗斯联邦, 48 ul. Pervomayskaya, Syktyvkar, 167000
I. Dvornikova
Institute of Chemistry, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
Email: chukichevaiy@mail.ru
俄罗斯联邦, 48 ul. Pervomayskaya, Syktyvkar, 167000
I. Fedorova
Institute of Chemistry, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
Email: chukichevaiy@mail.ru
俄罗斯联邦, 48 ul. Pervomayskaya, Syktyvkar, 167000
G. Chernysheva
Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center of the Russian Academy of Sciences
Email: chukichevaiy@mail.ru
俄罗斯联邦, 3 pr. Lenina, Tomsk, 634050
O. Aliev
Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center of the Russian Academy of Sciences
Email: chukichevaiy@mail.ru
俄罗斯联邦, 3 pr. Lenina, Tomsk, 634050
V. Smol’yakova
Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center of the Russian Academy of Sciences
Email: chukichevaiy@mail.ru
俄罗斯联邦, 3 pr. Lenina, Tomsk, 634050
A. Anishchenko
Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center of the Russian Academy of Sciences
Email: chukichevaiy@mail.ru
俄罗斯联邦, 3 pr. Lenina, Tomsk, 634050
A. Sidekhmenova
Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center of the Russian Academy of Sciences
Email: chukichevaiy@mail.ru
俄罗斯联邦, 3 pr. Lenina, Tomsk, 634050
M. Plotnikov
Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center of the Russian Academy of Sciences
Email: chukichevaiy@mail.ru
俄罗斯联邦, 3 pr. Lenina, Tomsk, 634050
A. Kutchin
Institute of Chemistry, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences
Email: chukichevaiy@mail.ru
俄罗斯联邦, 48 ul. Pervomayskaya, Syktyvkar, 167000
