Methods for determining neurotransmitter metabolism markers for clinical diagnostics
- 作者: Veselova I.1,2, Sergeeva E.1, Makedonskaya M.1,2, Eremina O.1,2, Kalmykov S.1,2, Shekhovtsova T.1
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隶属关系:
- Department of Chemistry
- National Research Centre “Kurchatov Institute”
- 期: 卷 71, 编号 12 (2016)
- 页面: 1155-1168
- 栏目: Reviews
- URL: https://journals.rcsi.science/1061-9348/article/view/182186
- DOI: https://doi.org/10.1134/S1061934816120108
- ID: 182186
如何引用文章
详细
Published data describing the current status and prospects for the development of clinical diagnostics of a number of neurodegenerative and neuroendocrine diseases associated with neurotransmitter balance disorders in a human body are generalized, systematized, and assessed in the review. Characteristics, advantages, and limitations of neuroimaging techniques and different diagnostic methods based on measuring concentrations of protein markers, catecholamines, and their metabolites are discussed. Prospects of the application of optical methods, such as fluorimetry and surface-enhanced Raman spectroscopy, to the development of sensor systems for the diagnosis of these diseases by the concentration of catecholamines and their metabolites in biological fluids are demonstrated.
作者简介
I. Veselova
Department of Chemistry; National Research Centre “Kurchatov Institute”
编辑信件的主要联系方式.
Email: irina.veselova@mail.ru
俄罗斯联邦, Moscow, 119991; Moscow, 123098
E. Sergeeva
Department of Chemistry
Email: irina.veselova@mail.ru
俄罗斯联邦, Moscow, 119991
M. Makedonskaya
Department of Chemistry; National Research Centre “Kurchatov Institute”
Email: irina.veselova@mail.ru
俄罗斯联邦, Moscow, 119991; Moscow, 123098
O. Eremina
Department of Chemistry; National Research Centre “Kurchatov Institute”
Email: irina.veselova@mail.ru
俄罗斯联邦, Moscow, 119991; Moscow, 123098
S. Kalmykov
Department of Chemistry; National Research Centre “Kurchatov Institute”
Email: irina.veselova@mail.ru
俄罗斯联邦, Moscow, 119991; Moscow, 123098
T. Shekhovtsova
Department of Chemistry
Email: irina.veselova@mail.ru
俄罗斯联邦, Moscow, 119991