Methods for determining neurotransmitter metabolism markers for clinical diagnostics
- Авторлар: Veselova I.1,2, Sergeeva E.1, Makedonskaya M.1,2, Eremina O.1,2, Kalmykov S.1,2, Shekhovtsova T.1
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Мекемелер:
- Department of Chemistry
- National Research Centre “Kurchatov Institute”
- Шығарылым: Том 71, № 12 (2016)
- Беттер: 1155-1168
- Бөлім: Reviews
- URL: https://journals.rcsi.science/1061-9348/article/view/182186
- DOI: https://doi.org/10.1134/S1061934816120108
- ID: 182186
Дәйексөз келтіру
Аннотация
Published data describing the current status and prospects for the development of clinical diagnostics of a number of neurodegenerative and neuroendocrine diseases associated with neurotransmitter balance disorders in a human body are generalized, systematized, and assessed in the review. Characteristics, advantages, and limitations of neuroimaging techniques and different diagnostic methods based on measuring concentrations of protein markers, catecholamines, and their metabolites are discussed. Prospects of the application of optical methods, such as fluorimetry and surface-enhanced Raman spectroscopy, to the development of sensor systems for the diagnosis of these diseases by the concentration of catecholamines and their metabolites in biological fluids are demonstrated.
Авторлар туралы
I. Veselova
Department of Chemistry; National Research Centre “Kurchatov Institute”
Хат алмасуға жауапты Автор.
Email: irina.veselova@mail.ru
Ресей, Moscow, 119991; Moscow, 123098
E. Sergeeva
Department of Chemistry
Email: irina.veselova@mail.ru
Ресей, Moscow, 119991
M. Makedonskaya
Department of Chemistry; National Research Centre “Kurchatov Institute”
Email: irina.veselova@mail.ru
Ресей, Moscow, 119991; Moscow, 123098
O. Eremina
Department of Chemistry; National Research Centre “Kurchatov Institute”
Email: irina.veselova@mail.ru
Ресей, Moscow, 119991; Moscow, 123098
S. Kalmykov
Department of Chemistry; National Research Centre “Kurchatov Institute”
Email: irina.veselova@mail.ru
Ресей, Moscow, 119991; Moscow, 123098
T. Shekhovtsova
Department of Chemistry
Email: irina.veselova@mail.ru
Ресей, Moscow, 119991
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