Identification and determination of antibacterial substances in drugs by capillary electrophoresis
- 作者: Bol’shakov D.1, Amelin V.1,2, Nikeshina T.1
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隶属关系:
- Federal Center for Animals Health
- Vladimir State University
- 期: 卷 71, 编号 1 (2016)
- 页面: 94-101
- 栏目: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/181395
- DOI: https://doi.org/10.1134/S1061934815110039
- ID: 181395
如何引用文章
详细
Methods of the quality control of finished dosage forms by capillary zone electrophoresis and micellar electrokinetic chromatography have been proposed. The optimum conditions for the separation and determination of different classes of antibacterial substances, penicillins, fluoroquinolones, nitrofurans, sulfanilamides, metronidazole, and chloramphenicol have been selected. The analytical range for the active ingredients of drugs was 1–1000 mg/g for solid and 0.001–0.50% for liquid drugs. The relative standard deviation of the results of analysis did not exceed 4%.
作者简介
D. Bol’shakov
Federal Center for Animals Health
Email: amelinvg@mail.ru
俄罗斯联邦, Yur’evets, Vladimir, 600901
V. Amelin
Federal Center for Animals Health; Vladimir State University
编辑信件的主要联系方式.
Email: amelinvg@mail.ru
俄罗斯联邦, Yur’evets, Vladimir, 600901; ul. Gor’kogo 87, Vladimir, 600000
T. Nikeshina
Federal Center for Animals Health
Email: amelinvg@mail.ru
俄罗斯联邦, Yur’evets, Vladimir, 600901