Identification and determination of antibacterial substances in drugs by capillary electrophoresis
- Авторлар: Bol’shakov D.1, Amelin V.1,2, Nikeshina T.1
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Мекемелер:
- Federal Center for Animals Health
- Vladimir State University
- Шығарылым: Том 71, № 1 (2016)
- Беттер: 94-101
- Бөлім: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/181395
- DOI: https://doi.org/10.1134/S1061934815110039
- ID: 181395
Дәйексөз келтіру
Аннотация
Methods of the quality control of finished dosage forms by capillary zone electrophoresis and micellar electrokinetic chromatography have been proposed. The optimum conditions for the separation and determination of different classes of antibacterial substances, penicillins, fluoroquinolones, nitrofurans, sulfanilamides, metronidazole, and chloramphenicol have been selected. The analytical range for the active ingredients of drugs was 1–1000 mg/g for solid and 0.001–0.50% for liquid drugs. The relative standard deviation of the results of analysis did not exceed 4%.
Авторлар туралы
D. Bol’shakov
Federal Center for Animals Health
Email: amelinvg@mail.ru
Ресей, Yur’evets, Vladimir, 600901
V. Amelin
Federal Center for Animals Health; Vladimir State University
Хат алмасуға жауапты Автор.
Email: amelinvg@mail.ru
Ресей, Yur’evets, Vladimir, 600901; ul. Gor’kogo 87, Vladimir, 600000
T. Nikeshina
Federal Center for Animals Health
Email: amelinvg@mail.ru
Ресей, Yur’evets, Vladimir, 600901
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