Synthesis, Antimicrobial Activity, and Behavioral Response Effects of N-Substituted 4-Aryl-2-Hydroxy-4-Oxobut-2-Enoic Acid Hydrazides and Their Metal Complexes
- Авторы: Pulina N.1, Kuznetsov A.1, Krasnova A.1, Novikova V.1
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Учреждения:
- Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
- Выпуск: Том 53, № 3 (2019)
- Страницы: 220-224
- Раздел: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245703
- DOI: https://doi.org/10.1007/s11094-019-01983-4
- ID: 245703
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Аннотация
N-Substituted 4-aryl-2-hydroxy-4-oxobut-2-enoic acid hydrazides and their complexes with Ni(II), Mn(II), Co(II), Cu(II), and Zn(II) were prepared. Their antimicrobial activity and behavioral response effects in mice were studied. Compounds with low acute toxicities and activities comparable to or exceeding those of the reference drugs were discovered.
Об авторах
N. Pulina
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: pulina-nata@mail.ru
Россия, Perm, Perm Krai, 614990
A. Kuznetsov
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: pulina-nata@mail.ru
Россия, Perm, Perm Krai, 614990
A. Krasnova
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: pulina-nata@mail.ru
Россия, Perm, Perm Krai, 614990
V. Novikova
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: pulina-nata@mail.ru
Россия, Perm, Perm Krai, 614990