Synthesis, Antimicrobial Activity, and Behavioral Response Effects of N-Substituted 4-Aryl-2-Hydroxy-4-Oxobut-2-Enoic Acid Hydrazides and Their Metal Complexes
- 作者: Pulina N.1, Kuznetsov A.1, Krasnova A.1, Novikova V.1
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隶属关系:
- Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
- 期: 卷 53, 编号 3 (2019)
- 页面: 220-224
- 栏目: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245703
- DOI: https://doi.org/10.1007/s11094-019-01983-4
- ID: 245703
如何引用文章
详细
N-Substituted 4-aryl-2-hydroxy-4-oxobut-2-enoic acid hydrazides and their complexes with Ni(II), Mn(II), Co(II), Cu(II), and Zn(II) were prepared. Their antimicrobial activity and behavioral response effects in mice were studied. Compounds with low acute toxicities and activities comparable to or exceeding those of the reference drugs were discovered.
作者简介
N. Pulina
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: pulina-nata@mail.ru
俄罗斯联邦, Perm, Perm Krai, 614990
A. Kuznetsov
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: pulina-nata@mail.ru
俄罗斯联邦, Perm, Perm Krai, 614990
A. Krasnova
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: pulina-nata@mail.ru
俄罗斯联邦, Perm, Perm Krai, 614990
V. Novikova
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: pulina-nata@mail.ru
俄罗斯联邦, Perm, Perm Krai, 614990