Enviar artigo por via de e-mail Synthesis, Antimicrobial Activity, and Behavioral Response Effects of N-Substituted 4-Aryl-2-Hydroxy-4-Oxobut-2-Enoic Acid Hydrazides and Their Metal Complexes
- Autores: Pulina N.1, Kuznetsov A.1, Krasnova A.1, Novikova V.1
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Afiliações:
- Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
- Edição: Volume 53, Nº 3 (2019)
- Páginas: 220-224
- Seção: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245703
- DOI: https://doi.org/10.1007/s11094-019-01983-4
- ID: 245703
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Resumo
N-Substituted 4-aryl-2-hydroxy-4-oxobut-2-enoic acid hydrazides and their complexes with Ni(II), Mn(II), Co(II), Cu(II), and Zn(II) were prepared. Their antimicrobial activity and behavioral response effects in mice were studied. Compounds with low acute toxicities and activities comparable to or exceeding those of the reference drugs were discovered.
Sobre autores
N. Pulina
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: pulina-nata@mail.ru
Rússia, Perm, Perm Krai, 614990
A. Kuznetsov
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: pulina-nata@mail.ru
Rússia, Perm, Perm Krai, 614990
A. Krasnova
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: pulina-nata@mail.ru
Rússia, Perm, Perm Krai, 614990
V. Novikova
Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation
Email: pulina-nata@mail.ru
Rússia, Perm, Perm Krai, 614990
