The Main Structural Types of Inhibitors of Matrix Metalloproteinases
- Авторлар: Kapranov L.1, Reznikov A.1, Klimochkin Y.1
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Мекемелер:
- Samara State Technical University
- Шығарылым: Том 51, № 3 (2017)
- Беттер: 175-181
- Бөлім: Search for New Drugs
- URL: https://journals.rcsi.science/0091-150X/article/view/244524
- DOI: https://doi.org/10.1007/s11094-017-1577-4
- ID: 244524
Дәйексөз келтіру
Аннотация
This review addresses the main structural types of matrix metalloproteinase (MMP) inhibitors - hydroxamic acid derivatives, sulfonamides, bisphosphonates, compounds combining phosphoryl and hydroxamate groups, and functional derivatives of phosphonic and phosphinic acids. The selectivity of the inhibitory actions of these substances in relation to different types of MMP and the potential for the practical application of these substances in cancer treatment are discussed.
Авторлар туралы
L. Kapranov
Samara State Technical University
Email: orgphosphorus@yandex.ru
Ресей, 244 Molodogvardeiskaya Street, Samara, 443100
A. Reznikov
Samara State Technical University
Хат алмасуға жауапты Автор.
Email: orgphosphorus@yandex.ru
Ресей, 244 Molodogvardeiskaya Street, Samara, 443100
Yu. Klimochkin
Samara State Technical University
Email: orgphosphorus@yandex.ru
Ресей, 244 Molodogvardeiskaya Street, Samara, 443100