The Main Structural Types of Inhibitors of Matrix Metalloproteinases
- 作者: Kapranov L.1, Reznikov A.1, Klimochkin Y.1
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隶属关系:
- Samara State Technical University
- 期: 卷 51, 编号 3 (2017)
- 页面: 175-181
- 栏目: Search for New Drugs
- URL: https://journals.rcsi.science/0091-150X/article/view/244524
- DOI: https://doi.org/10.1007/s11094-017-1577-4
- ID: 244524
如何引用文章
详细
This review addresses the main structural types of matrix metalloproteinase (MMP) inhibitors - hydroxamic acid derivatives, sulfonamides, bisphosphonates, compounds combining phosphoryl and hydroxamate groups, and functional derivatives of phosphonic and phosphinic acids. The selectivity of the inhibitory actions of these substances in relation to different types of MMP and the potential for the practical application of these substances in cancer treatment are discussed.
作者简介
L. Kapranov
Samara State Technical University
Email: orgphosphorus@yandex.ru
俄罗斯联邦, 244 Molodogvardeiskaya Street, Samara, 443100
A. Reznikov
Samara State Technical University
编辑信件的主要联系方式.
Email: orgphosphorus@yandex.ru
俄罗斯联邦, 244 Molodogvardeiskaya Street, Samara, 443100
Yu. Klimochkin
Samara State Technical University
Email: orgphosphorus@yandex.ru
俄罗斯联邦, 244 Molodogvardeiskaya Street, Samara, 443100