Enviar artigo por via de e-mail Fibrin- and Fibrinogenolytic Effect of Extracellular Proteinases of Microfungi Aspergillus alliaceus 7dN1 and A. terreus 2
- Autores: Osmolovskiy A.1,2, Klyagin S.1, Vashkevich T.1, Kurakov A.1, Kreyer V.1
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Afiliações:
- Faculty of Biology of M.V. Lomonosov Moscow State University
- Faculty of Biotechnology of M.V. Lomonosov Moscow State University
- Edição: Volume 57, Nº 4 (2023)
- Páginas: 298-300
- Seção: SHORT COMMUNICATIONS
- URL: https://journals.rcsi.science/0026-3648/article/view/138097
- DOI: https://doi.org/10.31857/S0026364823040086
- EDN: https://elibrary.ru/VVADYR
- ID: 138097
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Resumo
Proteolytic cleavage of fibrin and fibrinogen under the action of proteases of microfungi Aspergillus alliaceus 7dN1 and A. terreus 2 was carried out. It was shown that both enzymes can have strong α-fibrinogenase and moderate β-fibrinogenase activity, practically without affecting the γ-chains of these molecules. The products of cleavage in the time interval up to 60 min are polypeptides with a molecular weight of 15 kDa or less.
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Sobre autores
A. Osmolovskiy
Faculty of Biology of M.V. Lomonosov Moscow State University; Faculty of Biotechnology of M.V. Lomonosov Moscow State University
Autor responsável pela correspondência
Email: aosmol@mail.ru
Russia, Moscow; Russia, Moscow
S. Klyagin
Faculty of Biology of M.V. Lomonosov Moscow State University
Autor responsável pela correspondência
Email: sergey_klyagin@mail.ru
Russia, Moscow
T. Vashkevich
Faculty of Biology of M.V. Lomonosov Moscow State University
Autor responsável pela correspondência
Email: 12878853t@gmail.com
Russia, Moscow
A. Kurakov
Faculty of Biology of M.V. Lomonosov Moscow State University
Autor responsável pela correspondência
Email: kurakov57@mail.ru
Russia, Moscow
V. Kreyer
Faculty of Biology of M.V. Lomonosov Moscow State University
Autor responsável pela correspondência
Email: vkreyer@yandex.ru
Russia, Moscow
Bibliografia
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- Osmolovskiy A.A., Zvonareva E.S., Kreyer V.G. et al. Thrombolytic potential of the extracellular proteinase of micromycete Aspergillus terreus 2. Mikologiya i fitopatologiya. 2021. V. 55 (3). P. 225–228 (in Russ.). https://doi.org/10.31857/S0026364821030089
- Osmolovskiy A.A., Zvonareva E.S., Kreyer V.G. et al. The effect of micromycete extracellular proteases of Aspergillus genus on the proteins of haemostatic system. Russ. J. Bioorg. Chem. 2014. V. 40 (6). P. 634–639.
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- Zvonareva E.S., Osmolovskiy A.A., Kreier V.G. et al. Production of proteinase with plasmin-like and prekallikrein activating activity by the micromycete Aspergillus terreus. Appl. Biochem. Microbiol. 2018. V. 54 (2). P. 206–210. https://doi.org/10.1134/S0003683818020151
- Осмоловский А.А., Звонарева Е.С., Крейер В.Г. и др. (Osmolovskiy et al.) Секреция протеиназ с фибринолитической активностью микромицетами рода Aspergillus // Вестник Моск. ун-та. Сер. 16. Биол. 2018. Т. 73 (1). С. 39–42.
- Осмоловский А.А., Звонарева Е.С., Крейер В.Г. и др. (Osmolovskiy et al.) Тромболитический потенциал внеклеточной протеиназы микромицета Aspergillus terreus 2 // Микология и фитопатология. 2021. Т. 55. № 3. С. 225–228.
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