Email this article Fibrin- and Fibrinogenolytic Effect of Extracellular Proteinases of Microfungi Aspergillus alliaceus 7dN1 and A. terreus 2
- Authors: Osmolovskiy A.A.1,2, Klyagin S.D.1, Vashkevich T.V.1, Kurakov A.V.1, Kreyer V.G.1
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Affiliations:
- Faculty of Biology of M.V. Lomonosov Moscow State University
- Faculty of Biotechnology of M.V. Lomonosov Moscow State University
- Issue: Vol 57, No 4 (2023)
- Pages: 298-300
- Section: КРАТКИЕ СООБЩЕНИЯ
- URL: https://journals.rcsi.science/0026-3648/article/view/138097
- DOI: https://doi.org/10.31857/S0026364823040086
- EDN: https://elibrary.ru/VVADYR
- ID: 138097
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Abstract
Proteolytic cleavage of fibrin and fibrinogen under the action of proteases of microfungi Aspergillus alliaceus 7dN1 and A. terreus 2 was carried out. It was shown that both enzymes can have strong α-fibrinogenase and moderate β-fibrinogenase activity, practically without affecting the γ-chains of these molecules. The products of cleavage in the time interval up to 60 min are polypeptides with a molecular weight of 15 kDa or less.
About the authors
A. A. Osmolovskiy
Faculty of Biology of M.V. Lomonosov Moscow State University; Faculty of Biotechnology of M.V. Lomonosov Moscow State University
Author for correspondence.
Email: aosmol@mail.ru
Russia, Moscow; Russia, Moscow
S. D. Klyagin
Faculty of Biology of M.V. Lomonosov Moscow State University
Author for correspondence.
Email: sergey_klyagin@mail.ru
Russia, Moscow
T. V. Vashkevich
Faculty of Biology of M.V. Lomonosov Moscow State University
Author for correspondence.
Email: 12878853t@gmail.com
Russia, Moscow
A. V. Kurakov
Faculty of Biology of M.V. Lomonosov Moscow State University
Author for correspondence.
Email: kurakov57@mail.ru
Russia, Moscow
V. G. Kreyer
Faculty of Biology of M.V. Lomonosov Moscow State University
Author for correspondence.
Email: vkreyer@yandex.ru
Russia, Moscow
References
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