Antibodies to Glutamate Reversed the Amnesic Effects of Proinflammatory S100A9 Protein Fibrils in Aged C57Bl/6 Mice

M. A. Gruden; T. V. Davydova; V. G. Fomina; L. A. Vetrile; L. A. Morozova-Roche; R. D. E. Sewell

doi:10.1007/s10517-017-3632-2

Antibodies to Glutamate Reversed the Amnesic Effects of Proinflammatory S100A9 Protein Fibrils in Aged C57Bl/6 Mice

作者: Gruden M.¹, Davydova T.², Fomina V.², Vetrile L.², Morozova-Roche L.³, Sewell R.⁴
隶属关系:
1. P. K. Anokhin Research Institute of Normal Physiology
2. Research Institute of General Pathology and Pathophysiology
3. Department of Medical Biochemistry and Biophysics, Umea University
4. Cardiff School of Pharmacy and Pharmaceutical Sciences, Cardiff University
期: 卷 162, 编号 4 (2017)
页面: 430-432
栏目: Article
URL: https://journals.rcsi.science/0007-4888/article/view/238278
DOI: https://doi.org/10.1007/s10517-017-3632-2
ID: 238278

如何引用文章

全文:

开放存取

##reader.subscriptionAccessGranted##
受限制的访问

订阅存取

详细
作者简介
参考
统计

详细

Chronic intranasal administration of fibrillar structures of proinflammatory S100A9 protein impaired passive avoidance learning in old C57Bl/6 mice. Combined treatment with S100A9 fibrils and antibodies to glutamate was followed by an increase in horizontal locomotor activity of animals in the open-field test and did not disturb spatial memory.