Generation of Reactive Oxygen Species in Peripheral Blood Lymphocytes of Patients with Prostate Cancer
- 作者: Grekhova A.1, Gorbacheva L.1
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隶属关系:
- N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- 期: 卷 160, 编号 5 (2016)
- 页面: 709-711
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236909
- DOI: https://doi.org/10.1007/s10517-016-3256-y
- ID: 236909
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详细
The study revealed a two-fold elevation of ROS production in peripheral blood lymphocytes of the patients with prostate cancer (from 0.48±0.04 to 0.93±0.12 rel. units) together with significant variability of individual values. Hormone therapy had no effect on the mean and individual ROS levels. In contrast, organometallic cytostatics cisplatin and morfozol 2-fold increased ROS generation in lymphocytes of patients with prostate cancer above the enhanced level of this parameter determined by tumor growth.
作者简介
A. Grekhova
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: annagrekhova1@gmail.com
俄罗斯联邦, Moscow
L. Gorbacheva
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Email: annagrekhova1@gmail.com
俄罗斯联邦, Moscow