Generation of Reactive Oxygen Species in Peripheral Blood Lymphocytes of Patients with Prostate Cancer
- Авторы: Grekhova A.1, Gorbacheva L.1
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Учреждения:
- N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- Выпуск: Том 160, № 5 (2016)
- Страницы: 709-711
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236909
- DOI: https://doi.org/10.1007/s10517-016-3256-y
- ID: 236909
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Аннотация
The study revealed a two-fold elevation of ROS production in peripheral blood lymphocytes of the patients with prostate cancer (from 0.48±0.04 to 0.93±0.12 rel. units) together with significant variability of individual values. Hormone therapy had no effect on the mean and individual ROS levels. In contrast, organometallic cytostatics cisplatin and morfozol 2-fold increased ROS generation in lymphocytes of patients with prostate cancer above the enhanced level of this parameter determined by tumor growth.
Об авторах
A. Grekhova
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: annagrekhova1@gmail.com
Россия, Moscow
L. Gorbacheva
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Email: annagrekhova1@gmail.com
Россия, Moscow