Enviar artigo por via de e-mail Generation of Reactive Oxygen Species in Peripheral Blood Lymphocytes of Patients with Prostate Cancer
- Autores: Grekhova A.1, Gorbacheva L.1
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Afiliações:
- N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- Edição: Volume 160, Nº 5 (2016)
- Páginas: 709-711
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236909
- DOI: https://doi.org/10.1007/s10517-016-3256-y
- ID: 236909
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Resumo
The study revealed a two-fold elevation of ROS production in peripheral blood lymphocytes of the patients with prostate cancer (from 0.48±0.04 to 0.93±0.12 rel. units) together with significant variability of individual values. Hormone therapy had no effect on the mean and individual ROS levels. In contrast, organometallic cytostatics cisplatin and morfozol 2-fold increased ROS generation in lymphocytes of patients with prostate cancer above the enhanced level of this parameter determined by tumor growth.
Sobre autores
A. Grekhova
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Autor responsável pela correspondência
Email: annagrekhova1@gmail.com
Rússia, Moscow
L. Gorbacheva
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Email: annagrekhova1@gmail.com
Rússia, Moscow
