Generation of Reactive Oxygen Species in Peripheral Blood Lymphocytes of Patients with Prostate Cancer
- Авторлар: Grekhova A.1, Gorbacheva L.1
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Мекемелер:
- N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- Шығарылым: Том 160, № 5 (2016)
- Беттер: 709-711
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236909
- DOI: https://doi.org/10.1007/s10517-016-3256-y
- ID: 236909
Дәйексөз келтіру
Аннотация
The study revealed a two-fold elevation of ROS production in peripheral blood lymphocytes of the patients with prostate cancer (from 0.48±0.04 to 0.93±0.12 rel. units) together with significant variability of individual values. Hormone therapy had no effect on the mean and individual ROS levels. In contrast, organometallic cytostatics cisplatin and morfozol 2-fold increased ROS generation in lymphocytes of patients with prostate cancer above the enhanced level of this parameter determined by tumor growth.
Авторлар туралы
A. Grekhova
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Хат алмасуға жауапты Автор.
Email: annagrekhova1@gmail.com
Ресей, Moscow
L. Gorbacheva
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Email: annagrekhova1@gmail.com
Ресей, Moscow