PECULIARITIES OF MANAGEMENT IN WOMEN OF DIFFERENT AGE GROUPS WITH ABNORMAL UTERINE BLLEDING

Ключевые слова. Аномальное маточное кровотечение, гиперплазия эндометрия. Aim. To assess management of women with abnormal uterine bleeding (AUB), who underwent surgical hemostasis. Materials and methods. Seventy nine ambulatory and hospital medical records were analyzed. There were women of two age groups: group I - 39 women with stages 4 and 3b, group II - 40 women with stages 3a and 2 by "STRAW+10" classification. In patients of menopausal transition, cases of arterial hypertension, obesity and type 2 diabetes mellitus were fixed reliably more often, while hepatobiliary diseases were revealed with similar frequency in women of both groups. Six (15,3 %) women in group I, and eleven (27,5 %) women in group II had repeated hemorrhage. The interval between the first and the repeated episode of AUB in group I was 8,4 ± 1,6 months, but in group II - 5,6 ± 2,4 months ( p = 0,03). Results. While performing histological study of endometrium, presence of simple endometrial hyperplasia (EHP) without atopy was detected in 32 (82,5 %) patients of group I; in 7 (17,9 %) patients - deficient secretory endometrial transformation was observed. In women of group II there were 2 cases (5 %) of complicated EHP without atopy and 12 (30 %) cases of multiple endometrial polyposis, in the rest 23 cases (57,5 %) glandular and glandular-fibrous EHP was developed ( p = 0,02). Only 21 (53,8 %) patients of group I and 35 (87,5 %) patients of group II underwent ambulatory antirelapsing therapy. Patients of reproductive age received progesteron drugs - 12 (57 %), "Mirena" - 7 (33,3 %) and only 2 (9,5 %) women took combined oral contraceptives. Women of group II received therapy with gonadotropin-releasing hormone agonists for 3-4 months. Conclusions. Menstrual cycle disorders are the predisposing factor for AUB development. In most cases, simple endometrial hyperplasia is a morphological substrate of AUB. Rehabilitation measures are to be conducted for prevention of abnormal uterine bleeding

Abnormal uterine bleeding, endometrial hyperplasia