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Post a Comment Metabolic aspects of acute stage ischemic stroke
- Authors: Izhbuldina G.I.1, Novikova L.B.2, Timerbayeva D.A.1, Sharipova E.V.1, Murzabayeva R.V.1
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Affiliations:
- City Clinical Hospital № 18
- Bashkir State Medical University
- Issue: Vol 35, No 1 (2018)
- Pages: 5-11
- Section: Articles
- URL: https://journals.rcsi.science/PMJ/article/view/8663
- DOI: https://doi.org/10.17816/pmj3515-11
- ID: 8663
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Abstract
Aim. To study the influence of hyperglycemia on the course of ischemic stroke in its acute period.
Materials and methods. 116 patients with primary ischemic stroke, associated with arterial hypertension, and with no diabetes mellitus in anamnesis were examined. Fasting blood glucose, glycolyzed hemoglobin, immunoreactive insulin and C-peptide levels were determined.
Results. Raised levels of glycemia to 5.31 ± 0.68 mmol/l, C-peptide to 0.90 ± 0.31 nmol/l and decreased level of insulin to 9.38 ± 4.34 mcIU/ml were detected. C-peptide to insulin ratio values were reliably higher in patients with severe course of stroke (by 35.6 %, p < 0.05) and unfavorable outcome of disease (by 39.6 %, p < 0.05).
Conclusions. Development of ischemic stroke is accompanied by high blood C-peptide levels against the background of normo-and-hypoinsulinemia, hyperglycemia. Manifestation of disorders is connected with severity and clinical outcome of this disease.
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##article.viewOnOriginalSite##About the authors
G. I. Izhbuldina
City Clinical Hospital № 18
Author for correspondence.
Email: gulnara-ufa@list.ru
кандидат медицинских наук, заведующая неврологическим отделением для больных с ОНМК
Russian Federation, UfaL. B. Novikova
Bashkir State Medical University
Email: gulnara-ufa@list.ru
доктор медицинских наук, профессор, заведующая кафедрой неврологии и нейрохирургии ИДПО
Russian Federation, UfaD. A. Timerbayeva
City Clinical Hospital № 18
Email: gulnara-ufa@list.ru
кандидат медицинских наук, заведующая иммунологической лабораторией
Russian Federation, UfaE. V. Sharipova
City Clinical Hospital № 18
Email: gulnara-ufa@list.ru
заведующая клинико-диагностической лабораторией
Russian Federation, UfaR. V. Murzabayeva
City Clinical Hospital № 18
Email: gulnara-ufa@list.ru
врач-лаборант иммунологической лаборатории
Russian Federation, UfaReferences
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