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Post a Comment CYTOMEGALOVIRUS DETECTION FREQUENCY IN INFANTS BORN OWING TO USE OF AUXILIARY REPRODUCTIVE TECHNOLOGIES
- Authors: Permyakova AV1, Lvova II1, Makhmudova SE1
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Affiliations:
- Пермский государственный медицинский университет им. академика Е.А. Вагнера
- Issue: Vol 34, No 2 (2017)
- Pages: 51-55
- Section: Articles
- URL: https://journals.rcsi.science/PMJ/article/view/6787
- DOI: https://doi.org/10.17816/pmj34251-55
- ID: 6787
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Abstract
Aim. To determine the frequency of detecting cytomegaloviral infection (CMVI) in infants born as a result of extracorporal fertilization (ECF). Materials and methods. Medical documentation and examination of 46 infants under 1 year, who were born by means of ECF, were analyzed. To detect CMV DNA and determine its quantitative content, PCR in a real-time mode (test-system “AmpliSens® SMV-screen/monitor-FL” (Russia)) was used. Saliva and urine served as the study material. Results. CMV DNA, determined in the saliva and urine, indicated the following: in 78,3 % (36/46) of infants, no viral DNA was revealed in any of media. In 21,7 % (10/46) of infants, salivary CMV DNA was detected, in 17,4 % (8/46) - urinary. Viral load median of CMV DNA in the saliva was 5,5l g copies of DNA/ml (confidence interval, CI - 4,9; 6,1), in the urine - 4,6 lg copies of DNA/ml (CI - 4,0; 5,2) with no reliable difference for the studied media. Finally, the share of CMV-positive infants, born by means of ECF within the first year of life was 21,7 %. Conclusions. Infants, born owing to ECF, in 65,2 % of cases are premature; CMVI frequency, verified by PCR-positive salivary and urinary tests among them is 21,0 %.
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##article.viewOnOriginalSite##About the authors
A V Permyakova
Пермский государственный медицинский университет им. академика Е.А. Вагнера
Email: derucheva@mail.ru
кандидат медицинских наук, доцент кафедры детских инфекционных болезней 614000, г. Пермь, ул. Петропавловская, 26, тел. 8 902 474-04-80
I I Lvova
Пермский государственный медицинский университет им. академика Е.А. Вагнерадоктор медицинских наук, профессор, заведующая кафедрой детских инфекционных болезней 614000, г. Пермь, ул. Петропавловская, 26, тел. 8 902 474-04-80
S E Makhmudova
Пермский государственный медицинский университет им. академика Е.А. Вагнерастудентка V курса лечебного факультета 614000, г. Пермь, ул. Петропавловская, 26, тел. 8 902 474-04-80
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