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Post a Comment Restoration of sinus rhythm and left ventricular function in a patient with long-standing persistent atrial fibrillation and chronic heart failure with reduced left ventricular ejection fraction
- Authors: Khuziakhmetov R.D.1, Orekhova E.N.2, Kadyraliev B.K.1, Khlynova O.V.2
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Affiliations:
- Federal Center for Cardiovascular Surgery named after S.G. Sukhanov
- Ye.A. Vagner Perm State Medical University
- Issue: Vol 42, No 6 (2025)
- Pages: 167-175
- Section: Clinical case
- URL: https://journals.rcsi.science/PMJ/article/view/381428
- DOI: https://doi.org/10.17816/pmj426167-175
- ID: 381428
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Abstract
The objective of the study is to evaluate the effect of sinus rhythm (SR) restoration in a patient with long-standing persistent atrial fibrillation (AF) and chronic heart failure with reduced ejection fraction (HFrEF) of the left ventricle (LV) on the progression of CHF and LV function.
The benefits of selecting a "rhythm control" strategy (restoration and maintenance of SR) in patients with long-standing persistent AF and HFrEF remain debated. However, in some cases, even with significantly reduced LV ejection fraction (EF), SR restoration may improve the clinical status, enhance LV systolic function, and reduce CHF severity. As an illustration, we present a clinical case of a patient with long-standing persistent AF and HFrEF where SR restoration resulted in normalized LV EF and alleviated CHF symptoms.
In long-standing persistent tachyarrhythmic AF with HFrEF, achieving adequate heart rate control and managing CHF symptoms through pharmacotherapy alone is challenging. A rhythm control strategy in patients with long-standing persistent AF and HFrEF can be successfully implemented, resulting in significant improvement in the functional status, reverse remodeling of the left atrium and LV, and normalization of LV systolic function.
About the authors
R. D. Khuziakhmetov
Federal Center for Cardiovascular Surgery named after S.G. Sukhanov
Author for correspondence.
Email: rustam-huziahmetov@yandex.ru
ORCID iD: 0009-0001-2835-9571
Cardiovascular Surgeon
Russian Federation, PermE. N. Orekhova
Ye.A. Vagner Perm State Medical University
Email: rustam-huziahmetov@yandex.ru
ORCID iD: 0000-0002-7097-8771
DSc (Medicine), Associate Professor of the Department of Hospital Therapy and Cardiology
Russian Federation, PermB. K. Kadyraliev
Federal Center for Cardiovascular Surgery named after S.G. Sukhanov
Email: rustam-huziahmetov@yandex.ru
ORCID iD: 0000-0002-4007-7665
DSc (Medicine), Head of the Department for Organ and Tissue Donation Coordination, Cardiovascular Surgeon
Russian Federation, PermO. V. Khlynova
Ye.A. Vagner Perm State Medical University
Email: rustam-huziahmetov@yandex.ru
ORCID iD: 0000-0003-4860-0112
DSc (Medicine), Professor, Corresponding Member of the Russian Academy of Sciences, Head of the Department of Hospital Therapy and Cardiology
Russian Federation, PermReferences
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