Improvement of wound treatment in diabetic foot syndrome by a physicochemical method

Cover Page

Cite item

Full Text

Abstract

Objective. To improve the treatment results of patients with diabetic foot syndrome having severe lesions complicated by purulent wounds of the foot and lower leg employing an improved ultrasound wound treatment method.

Materials and methods. The study is based on the examination and treatment data of 123 patients with severe diabetic foot syndrome, complicated by purulent wounds of the foot and lower leg, who received inpatient treatment at the Bukhara State Medical Institute Clinic for the period from 2024 to 2025.

Results. In the treatment of severe diabetic foot syndrome complicated by purulent wounds of the foot and lower leg, an established approach using combined ultrasound wound treatment with a 25 % dimexide solution and an electroactivated solution – A is more effective than ultrasound treatment of a wound with saline solution or using 25 % dimexide solution. This combined approach demonstrated acceleration of healing processes, reduction of intoxication indicators by an average of 2–4 days, elimination of major amputation cases, significant reduction in amputation rates: shin-level amputation from 18.9 % to 7.5 %, atypical foot resection from 24.3 % to 15.0 %, reamputations from 5.4 % to 0 %, postoperative stump suppuration from 5.4 % to 2.5 % compared to subgroup II A.

Conclusions. The use of ultrasound wound treatment with 25 % dimexide solution combined with electroactivated solution A for purulent wounds in diabetic foot syndrome is a more effective method which reduced the average hospital stay from9,6 ± 1,3 до 7,1 ± 0,8 days.

About the authors

B. B. Safoev

Bukhara State Medical Institute named after Abu Ali ibn Sino

Email: docboltaevtimur@mail.ru
ORCID iD: 0000-0003-4573-6436

DSc (Medicine), Professor, Head of the Department of General Surgery

Uzbekistan, Bukhara

T. Sh. Boltaev

Bukhara State Medical Institute named after Abu Ali ibn Sino

Author for correspondence.
Email: docboltaevtimur@mail.ru
ORCID iD: 0000-0002-8842-8516

PhD (Medicine), Associate Professor of the Department of General Surgery

Uzbekistan, Bukhara

Sh. M. Khamroev

Bukhara State Medical Institute named after Abu Ali ibn Sino

Email: docboltaevtimur@mail.ru
ORCID iD: 0009-0007-6341-4728

Independent Degree Candidate for the Department of General Surgery

Uzbekistan, Bukhara

B. B. Safoev

Bukhara State Medical Institute named after Abu Ali ibn Sino

Email: docboltaevtimur@mail.ru
ORCID iD: 0009-0005-4117-1572

PhD (Medicine), Assistant of the Department of General Surgery

Uzbekistan, Bukhara

References

  1. Есипов А.В., Алехнович А.В., Мусаилов В.А., Маркевич П.С., Потапов В.А. Актуальные проблемы диагностики синдрома диабетической стопы. Вестник Нацио¬нального медико-хирур¬гического центра им. Н.И. Пирогова 2023; 18 (2): 115–120. doi: 10.25881/20728255_2023_18_2_115 / Esipov A.V., Alexnovich A.V., Musailov V.A., Markevich P.S., Potapov V.A. Actual problems of diagnosis of diabetic foot syndrome. Bulletin of the National Medical and Surgical center N.I. Pirogov 2023; 18 (2): 115–120. doi: 10.25881/20728255_2023_18_2_115 (in Russian).
  2. Галстян Г.Р., Токмакова А.Ю., Бондаренко О.Н., Ситкин И.И., Пряхина К.Ю., Митиш В.А., Доронина Л.П. Заболевания артерий нижних конечностей у пациентов с сахарным диабетом: состояние проблемы и перспективы лечения. Сахарный диабет 2011; 14 (1): 74–80. doi: 10.14341/2072-0351-6253 / Galstyan G.R., Tokmakova A.Yu., Bondarenko O.N., Sitkin I.I., Pryaxina K.Yu., Mitish V.A., Doronina L.P. Diseases of the arteries of the lower extremities in patients with diabetes mellitus: the state of the problem and treatment prospects. Saxarniy diabet 2011; 14 (1): 74–80. doi: 10.14341/2072-0351-6253 (in Russian).
  3. Safoev B.B., Nazarov J.R., Boltaev T.Sh. Differential approach of endovascular intervention in the treatment of patients with critical lower limb ischemia with diabetes. 中华劳动卫生职业病杂志2022年13月第40卷第13期Chin J Ind Hyg Occup Dis 2022; 838–844.
  4. Boltaev T.Sh. Effectiveness of endovascular treatment for obliterating atherosclerosis on the background of diabetes mellitus. American Journal of Pediatric Medicine and Health Sciences 2023; 1 (9): 2993–2149.
  5. Яровенко А.М., Ступак В.С., Люцко В.В., Кораблев В.Н., Димова О.А. Ампутации нижних конечностей при синдроме диабетической стопы: вопросы организации раннего выявления и профилактики осложнений (обзор литературы). Современные проблемы здравоохранения и медицинской статистики 2024; 1: 1115–1134. doi: 10.24412/2312-2935-2024-1-1115-1134 / Yarovenko A.M., Stupak V.S., Lyusko V.V., Korablev V.N., Dimova O.A. Lower limb amputations in diabetic foot syndrome: issues of organisation of early detection and prevention of complications (literature review). Current problems of health care and medical statistics 2024; 1: 1115–1134. doi: 10.24412/2312-2935-2024-1-1115-1134 (in Russian).
  6. Казиев У.К., Мусаев У.С., Иманкулова А.С., Миклухин Д.С. Опыт применения ультра-звуковой кавитации в лечении ран у пациентов с гнойно-некротическими осложнениями синдрома диабетической стопы. Раны и раневые инфекции. Журнал им. проф. Б.М. Кос-тю¬чёнка 2024; 11 (2): 30–36. doi: 10.25199/2408-9613-2024-11-2-28-34 / Kaziev U.K., Musaev U.S., Imankulova A.S., Mikluxin D.S. Ultrasonic cavitation for managing wounds in patients with purulent-necrotic complications of diabetic foot syndrome. Wounds and wound infections. The prof. B.M. Kostyuchenok journal 2024; 11 (2): 30–36. doi: 10.25199/2408-9613-2024-11-2-28-34 (in Russian).
  7. Митиш В.А., Пасхалова Ю.С., Муньос Сэпэда П.А., Ушаков А.А., Блатун Л.А., Борисов И.В., Магомедова С.Д. Ультразвуковая кавитация в лечении нейроишемической формы синдрома диабетической стопы при наличии биопленочных форм бактерий (обзор литературы). Раны и раневые инфекции. Журнал им. проф. Б.М. Костючёнка 2020; 7 (3): 20–31. doi: 10.25199/2408-9613-2020-7-3-20-31 / Mitish V.A., Paskhalova Yu.S., Munioz Sepeda P.A., Ushakov A.A., Blatun L.A., Borisov I.V., Magomedova S.D. Ultrasonic cavitation in the treatment of neuro-ischemic diabetic foot the presence of biofilm forms of bacteria (literature review). Wounds and wound infections. The prof. B.M. Kostyuchenok journal 2020; 7 (3): 20–31. doi: 10.25199/2408-9613-2020-7-3-20-31 (in Russian).
  8. Гурьева И.В. Возможности местного лечения диабетических поражений стоп. Русский медицинский журнал 2002; 10 (11): 509–512. / Guryeva I.V. Possibilities of local treatment of diabetic foot lesions. RJM 2002; 10 (11): 509–512 (in Russian).
  9. Привольнев В.В., Каракулина Е.В. Основные принципы местного лечения ран и раневой инфекции. Клиническая микробиология и антимикробная химиотерапия 2011; 13 (3): 214–222. / Privolnev V.V., Karakulina E.V. Basic principles of local treatment of wounds and wound infection. Clinical Microbiology and Antimicrobial Chemotherapy 2011; 13 (3): 214–222. EDN: ODSQXP (in Russian).
  10. Липатов К.В., Сопромадзе М.А., Емельянов А.Ю., Канорский И.Д. Использование физических методов в лечении гнойных ран (обзор литературы). Хирургия. Журнал им. Н.И. Пирогова 2001; 10: 56–61. / Lipatov K.V., Sopromadze M.A., Emelyanov A. Yu., Kanorskiy I.D. Use of physical methods in the treatment of purulent wounds (literature review). Surgery. N.I. Pirogov Journal 2001; 10: 56–61 (in Russian).

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2025 Eco-Vector

License URL: https://eco-vector.com/for_authors.php#07
 


Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).