PERIOPERATIVE HEMODYNAMIC CHANGES IN PATIENTS WITH METABOLIC SYNDROME WHILE PERFORMING CHOLECYSTECTOMY FROM MINI-APPROACH

Aim. The aim of the study was to ground an optimal variant of anesthetic management when performing cholecystectomy from mini-approach in patients with metabolic syndrome. Materials and methods. The results of studying hemodynamic indices in 90 patients during cholecystectomy from mini-approach in conditions of anesthetic management using “Isoflurane” or intravenous anesthesia on the basis of “Propofol” are presented in the paper. All patients underwent general clinical and special methods of investigation; in the perioperative period hemodynamic indices were monitored and additionally, the basic hemodynamic indices were estimated using calculated method. Results. It was detected while analyzing hemodynamics that in patients with metabolic syndrome, the initial systolic, diastolic and mean pressure was by 30 % higher versus the control group. The calculated indices such as stroke volume, circulatory minute volume, cardiac index were initially reduced (stroke volume - by 39 %, circulatory minute volume - by 37 %, cardiac index - by 44 %) in patients with metabolic syndrome as compared to the control group at all the stages of observation. Conclusions. Anesthetic management on the basis of “Propofol” changes to a lesser extent hemodynamic profile in patients with metabolic syndrome when performing cholecystectomy from mini-approach. Irrespective of the type of anesthetic management, maximum changes in hemodynamics are observed at the beginning of anesthesia in all patients with metabolic syndrome.

Metabolic syndrome, hemodynamics, anesthetic management, cholecystectomy