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Post a Comment Papillary microcarcinoma in three generations of the first degree relatives
- Authors: Tsurkan A.A.1, Karpova A.V.1, Tsurkan A.Y.2
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Affiliations:
- Voronezh State Medical University named after N. N. Burdenko
- Voronezh Regional Clinical Hospital No. 1
- Issue: Vol 41, No 4 (2024)
- Pages: 161-167
- Section: Clinical case
- URL: https://journals.rcsi.science/PMJ/article/view/267887
- DOI: https://doi.org/10.17816/pmj414161-167
- ID: 267887
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Abstract
Family papillary microcarcinoma of the thyroid gland is observed in 3–10 % of patients with cancer from follicular epithelial cells. Diagnosis and treatment are controversial. Three patients from the same family of the first degree of kinship were operated for family papillary microcarcinoma of the thyroid gland in Voronezh Regional Clinical Hospital No. 1. Only the first patient complained of the neck deformity, her son and granddaughter had an asymptomatic course of the disease. Metastases to the lymph nodes of the neck and bilateral localization of the tumor were not revealed. In the third generation, multifocal tumor growth was diagnosed at the age of 19. All patients underwent thyroidectomy. In the first patient, the period of relapse–free follow-up after surgery was 18 years, in the second and third – 5 years.
In the family form of papillary thyroid carcinoma, we consider active screening of relatives justified since the disease in the new generation may develop at a younger age and with the risk of multifocal thyroid damage even in microcarcinomas.
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##article.viewOnOriginalSite##About the authors
A. A. Tsurkan
Voronezh State Medical University named after N. N. Burdenko
Email: alexandertsu@yandex.ru
ORCID iD: 0000-0003-1814-9260
Student
Russian Federation, VoronezhA. V. Karpova
Voronezh State Medical University named after N. N. Burdenko
Email: alexandertsu@yandex.ru
ORCID iD: 0000-0001-9551-6381
Vice-Rector for International Affairs, PhD (Medicine). Associate Professor
Russian Federation, VoronezhA. Yu. Tsurkan
Voronezh Regional Clinical Hospital No. 1
Author for correspondence.
Email: alexandertsu@yandex.ru
ORCID iD: 0000-0001-9319-717X
PhD (Medicine), Associate Professor
Russian Federation, VoronezhReferences
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