Modern prospects for using polyene unsaturated fatty acids in obstetrics and gynecology

Cover Page

Cite item

Full Text

Abstract

Unsaturated fatty acids is the key block of cellular membranes, they determine the specificity of high-differentiated cells and are the precursors of eicosanoid synthesis (prostaglandins, thromboxanes, leukotrienes). A marked antiinflammatory, antisclerotic, antiarrhythmic, anticoagulant, neuroprotective and other effects of omega-3 polyunsaturated fatty acids, established in biochemical and experimental studies, stimulated implementation of a large number of epidemiological and clinical investigations. Successful application of polyunsaturated fatty acids in cardiology, neurology and other fields of therapy focuses on such spheres as obstetrics and gynecology.

About the authors

Michail A. Kiselev

City Clinical Hospital № 3

Author for correspondence.
Email: michail.kiselev@mail.ru
SPIN-code: 7098-2877

Врач акушер-гинеколог

Russian Federation, Tambov

Natalia B. Repina

Ryazan State Medical University named after Academician I.P. Pavlov

Email: nrepina62@gmail.com

канд. мед. наук, доцент кафедры акушерства и гинекологии

Russian Federation, Ryazan

Julia S. Kiseleva

Railway station Tambov “RZhD-Medicine” Polyclinic № 3, Michurinsk

Email: yulia.kiseleva1990@mail.ru

Врач кардиолог

Russian Federation, Tambov

References

  1. Ганчар Е.П., Кажина М.В., Яговдик И.Н. Клиническая значимость омега-3 ПНЖК полиненасыщенных жирных кислот в акушерстве. Журнал Грозненского государствен-ного медицинского университета 2012; 38 (2): 7–10.
  2. Зайцева Л.В., Нечаев А.П. Полиненасыщенные жирные кислоты в питании: современный взгляд. Пищевая промышленность 2014; 4: 14–19.
  3. Коваль Г.Д. Обоснование подходов к лечению бесплодия у женщин с эндометриозом в зависимости от иммунологических показателей. Universum: медицина и фармакология 2015; 19 (7–8): 1–13.
  4. Репина Н.Б., Бен Салха М. Актуальность проблемы спаечного процесса в малом тазу, его последствия и роль недифференцированной дисплазии соединительной ткани в его развитии. Российский медико-биологический вестник им. акад. И.П. Павлова 2016; 24 (1): 155–160.
  5. Тохириён Б., Протасова Л.Г. Оценка значимости жирно-кислотного состава растительных масел для здорового питания. Известия Уральского государственного экономического университета 2014; 55 (5): 115–119.
  6. Abokhrais I.M., Saunders P.T.K., Denison F.C., Doust A., Williams L., Horne A.V. A pilot randomised double blind controlled trial of the efficacy of purified fatty acids for the treatment of women with endometriosis-associated pain (PurFECT): study protocol. Pilot and feasibility studies 2018; 83 (4): 274–278.
  7. Appleton K.M., Sallis H.M., Perry R., Ness A.R., Churchill R. Omega-3 fatty acids for depression in adults. Cochrane Database of Systematic Reviews 2015; 11: 28–29.
  8. Bernard J.Y. Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants. American Journal of Clinical Nutrition 2018; 108 (1): 92–100.
  9. Brasky T.M., Moysich K.B., Cohn D.E., White E. Non-steroidal anti-inflammatory drugs and endometrial cancer risk in the VITamins And Lifestyle (VITAL) cohort. Gynecol Oncol 2013; 128: 113–119.
  10. Brasky T.M., Rodabough R.J., Liu J. Long-chain ω-3 fatty acid intake and endometrial cancer risk in the Women's Health Initiative. Am J Clin Nutr 2015; 101(4): 824–834.
  11. Cholewski M. A Comprehensive review of chemistry, sources and bioavailability of omega-3 fatty acids. Nutrients 2018; 10–11: 1662.
  12. Gao L., Lin L., Shan N., Ren C.-Y., Long X., Sun Y.-H., Wang L. The impact of omega-3 fatty acid supplementation on glycemic control in patients with gestational diabetes: a systematic review and meta-analysis of randomized controlled studies. The Journal of Maternal-Fetal & Neonatal Medicine 2018. doi: 10.1080/14767058.2018.1526916
  13. Jackson K.H., Harris W.S. A prenatal DHA test to help identify women at increased risk for early preterm birth: a proposal. Nutrients 2018; 10: 1933.
  14. Karakas D.O., Yigitler C., Gulec B., Kucukodaci Z., Ipcioglu O.M., Akin M.L. Comparison of 4 % icodextrin and omega 3 Fatty acids in prevention of peritoneal adhesions. Indian J Surg 2012; 76 (3): 181–186.
  15. Krakowsky R.H.E., Tollefsbol T.O. Impact of Nutrition on Non-Coding RNA Epigenetics in Breast and Gynecological Cancer. Frontiers in nutrition 2015. doi: 10.3389/fnut.2015.00016
  16. Kuper S.G., Abramovici A.R., Jauk V.C., Harper L.M., Biggio J.R., Tita A.T. The effect of omega-3 supplementation on pregnancy outcomes by smoking status. Am J Obstet Gynecol 2017; 217(4): 476.e1–476.e6.
  17. Lindsay K.L., Buss C., Wadhwa P.D., Entringer S. The interplay between maternal nutrition and stress during pregnancy: issues and considerations. Annals of Nutrition & Metabolism 2017; 70 (3): 191–200.
  18. Maisonneuve E. Mode de vie et règles hygiénodiététiques pour la prévention de la prématurité spontanée chez la femme enceinte asymptomatique. Journal de Gynécologie Obstétrique et Biologie de la Reproduction 2016; 45: 1231–1246.
  19. Middleton P., Gomersall J.C., Gould J.F., Shepherd E., Olsen S.F., Makrides M. Omega-3 fatty acid addition during pregnancy. Cochrane Database of Systematic Reviews 2018, 11: CD003402. doi: 10.1002/14651858.CD003402
  20. Missmer S.A., Chavarro J.E., Malspeis S., Bertone-Johnson E.R., Hornstein M.D., Spiegelman D., Barbieri R.L., Willett W.C., Hankinson S.E. A prospective study of dietary fat consumption and endometriosis risk. Hum Reprod 2010; 25 (6): 1528–1535.
  21. Mozurkewich E.L., Clinton C.M., Chilimigras J.L., Hamilton S.E., Allbaugh L.J., Berman D.R., Marcus S.M., Romero V.C., Treadwell M.C., Keeton K.L., Vahratian A.M., Schrader R.M., Ren J., Djuric Z. The mothers, omega-3, and mental health study: a double-blind, randomized controlled trial. American Journal of Obstetrics and Gynecology 2013; 208 (4): 313.
  22. Mumford S.L., Chavarro J.E., Zhang C., Perkins N.J., Sjaarda L.A., Pollack A.Z., Schliep K.C., Michels K.A., Zarek S.M., Plowden T.C., Radin R.G., Messer L.C., Frankel R.A., Wactawski-Wende J. Dietary fat intake and reproductive hormone concentrations and ovulation in regularly menstruating women. American journal of clinical nutrition 2016; 103 (3): 868–877.
  23. Nadjarzadeh A., Dehghani F.R., Vaziri N., Daneshbodi H., Lotfi M.H., Mozaffari-Khosravi H. The effect of omega-3 supplementation on androgen profile and menstrual status in women with polycystic ovary syndrome: A randomized clinical trial. Iranian Journal of Reproductive Medicine 2013; 11 (8): 665–672.
  24. Nehra D., Le H.D., Fallon E.M., Carlson S.J., Woods D., White Y.A., Pan A.H., Guo L., Rodig S.J., Tilly J.L., Rueda B.R., Puder M. Prolonging the female reproductive lifespan and improving egg quality with dietary omega-3 fatty acids. Aging Cell 2012; 11 (6): 1046–1054.
  25. Opiyo R.O., Nyasulu P.S., Koigi R.K., Obondo A., Ogoyi D., Kogi-Makau W. Effect of fish oil omega-3 fatty acids on reduction of depressive symptoms among HIV-seropositive pregnant women: a randomized, double-blind controlled trial. Annals of General Psychiatry 2018; 17: 49. doi: 10.1186/s12991-018-0220-4
  26. Saccone G., Saccone I., Berghella V. Omega-3 long-chain polyunsaturated fatty acids and fish oil supplementation during pregnancy: which evidence? J Matern Fetal Neonatal Med 2016; 29 (15): 2389–2397.
  27. Sokoła-Wysoczańska E., Wysoczański T., Wagner J., Czyż K., Bodkowski R., Lochyński S., Patkowska-Sokoła B. Polyunsaturated fatty acids and their potential therapeutic role in cardiovascular system disorders-A review. Nutrients 2018; 10 (10): 1561.
  28. Tomio K., Kawana K., Taguchi A., Isobe Y., Iwamoto R., Yamashita A., Kojima S., Mori M., Nagamatsu T., Arimoto T., Oda K., Osuga Y., Taketani Y., Kang J.X., Arai H., Arita M., Kozuma S., Fujii T. Omega-3 polyunsaturated fatty acids suppress the cystic lesion formation of peritoneal endometriosis in transgenic mouse models. PLoS One 2013; 8 (9): e73085.
  29. Vaz J.D.S., Farias D.R., Adegboye A.R.A., Nardi A.E., Kac G. Omega-3 supplementation from pregnancy to postpartum to prevent depressive symptoms: a randomized placebo-controlled trial. BMC Pregnancy and Childbirth 2017; 17 (1): 180.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2019 Kiselev M.A., Repina N.B., Kiseleva J.S.

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
 


Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).