Email this article Changing of pulmonary artery diameter in accordance with severity of COVID-19 (assessment based on non-contrast computer tomography)
- Authors: Aliev A.F.1,2, Kudryavtsev N.D.1,3, Petraikin A.V.3, Artyukova Z.R.3, Shkoda A.S.4, Morozov S.P.3
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Affiliations:
- L.A. Vorokhobov Municipal Clinical Hospital No 67 of the Moscow Health Department
- The Moscow Research and Clinical Center for Tuberculosis Control of the Moscow Health Department
- Moscow Center for Diagnostics and Telemedicine
- Vorokhobov City Clinical Hospital No. 67
- Issue: Vol 2, No 3 (2021)
- Pages: 249-260
- Section: Original Study Articles
- URL: https://journals.rcsi.science/DD/article/view/76726
- DOI: https://doi.org/10.17816/DD76726
- ID: 76726
Cite item
Abstract
BACKGROUND: Computed tomography is the method of choice for assessing the volume of lung damage in viral pneumonia, including those associated with COVID-19. In addition, computed tomography can determine the main vessels size of the thorax. This allowed us to analyze the relationship between the severity of COVID-19 and the changes in the diameters of the pulmonary artery (PA) and ascending aorta (Ao). Dilation of the PA is a sign of pulmonary hypertension. The study of these patterns may be of clinical significance in determining the treatment tactics and prognosis of the course of COVID-19 disease.
AIM: To evaluate the relationship between PA diameter and the severity of the COVID-19 course in patients of different ages.
MATERIALS AND METHODS: This study is a single-centered, cross-section, continuous, uncontrolled study performed on a group of patients (n=511, 267 men, median 59 years, IQR 49.0–65.0, ages 31–84 years) who were treated in a temporary hospital to treat patient with COVID-19. During hospitalization all patients were examined by CT scan of the chest. All studies were carried out using a mobile CT scan system Airo TruCT (Stryker, USA). The degree of damage to the lung tissue was assessed using the CT volume scale 1–4. Measurement of the LA and Ao diameters was carried out using standard instruments of the radiologist’s CT workstation perpendicular to the long axis of the vessel.
RESULTS: The following statistically significant regularities were obtained: the detection of a dilated pulmonary artery (PA) and an increased PA/Ao ratio correlated to an increase in the degree of lung damage in COVID-19 (Kruskal-Wallis test, K-W p <0.001; median test, MT p <0.001), the diameter of the ascending aorta (Ao) significantly increases with the patient’s age (K-W p <0.001; MT p <0.001). An insignificant correlation between an increase in the diameter of the pulmonary artery (PA) and the patient’s age (K-W p=0.094; MT p=0.311) and an insignificant correlation between detection of a change in aortic (Ao) diameter and the degree of lung damage (K-W p=0.061; MT p=0.165) were shown. In groups with a severe course of the disease and a large volume of lung lesions (CT-3 and CT-4), a significantly greater number of patients with signs of pulmonary hypertension (detection of the dilated pulmonary artery: 29 mm and more) was shown for all age groups.
CONCLUSION: The study showed that PA dilatation and increased PA/Ao diameter ratio were significantly associated with increased pulmonary lesion volume in COVID-19 in all age groups.
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##article.viewOnOriginalSite##About the authors
Alexander F. Aliev
L.A. Vorokhobov Municipal Clinical Hospital No 67 of the Moscow Health Department; The Moscow Research and Clinical Center for Tuberculosis Control of the Moscow Health Department
Email: alijealex83@gmail.com
ORCID iD: 0000-0003-3282-0567
SPIN-code: 7891-9314
MD, Cand. Sci. (Med.)
Russian Federation, 2/44, Salyama Adilya street, 123423 Moscow; 10 c1, Stromynka Street, 107014 MoscowNikita D. Kudryavtsev
L.A. Vorokhobov Municipal Clinical Hospital No 67 of the Moscow Health Department; Moscow Center for Diagnostics and Telemedicine
Email: n.kudryavtsev@npcmr.ru
ORCID iD: 0000-0003-4203-0630
SPIN-code: 1125-8637
diagnostic radiologist, junior researcher
Russian Federation, 2/44, Salyama Adilya street, 123423 Moscow; 24 с1, Petrovka street, 127051 MoscowAlexey V. Petraikin
Moscow Center for Diagnostics and Telemedicine
Email: alexeypetraikin@gmail.com
ORCID iD: 0000-0003-1694-4682
SPIN-code: 6193-1656
MD, Cand. Sci. (Med.), Associate Professor, leading researcher, diagnostic radiologist
Russian Federation, 24 с1, Petrovka street, 127051 MoscowZlata R. Artyukova
Moscow Center for Diagnostics and Telemedicine
Email: z.artyukova@npcmr.ru
ORCID iD: 0000-0003-2960-9787
SPIN-code: 7550-2441
MD, junior researcher, radiologist
Russian Federation, 24 с1, Petrovka street, 127051 MoscowAndrey S. Shkoda
Vorokhobov City Clinical Hospital No. 67
Email: gkb67@zdrav.mos.ru
ORCID iD: 0000-0002-9783-1796
MD, Dr. Sci. (Med.), Professor, doctor of the highest qualification category in the specialty, chief physician
Russian Federation, 2/44, Salama Adil street, 123423 MoscowSergey P. Morozov
Moscow Center for Diagnostics and Telemedicine
Author for correspondence.
Email: morozov@npcmr.ru
ORCID iD: 0000-0001-6545-6170
SPIN-code: 8542-1720
MD, Dr. Sci. (Med.), Professor
Russian Federation, 24 с1, Petrovka street, 127051 MoscowReferences
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