Glycation, antiglycation, and deglycation: Their role in aging mechanisms and geroprotective effects (literature review)


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Abstract

The biochemistry of glycation and its role in the disruption of cell metabolism and development of age-related pathologies have been reviewed in this manuscript based on literature data published, for the most part, in the last 5 years. The effects of antiglycation and deglycation actions of endogenous enzymes, as well as of exogenous chemical compounds of natural and synthetic nature on the process of aging, were evaluated.

About the authors

V. V. Emel’yanov

Ural Federal University named after the first President of Russia B.N. Yeltsin

Author for correspondence.
Email: evvd@list.ru
Russian Federation, Yekaterinburg, 620002

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