Enviar artigo por via de e-mail The New Plant Expression System for the Development of Vaccines against Papillomaviruses
- Autores: Salyaev R.K.1, Rekoslavskaya N.I.1,2, Stolbikov A.S.1
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Afiliações:
- Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch, Russian Academy of Sciences
- Irkutsk Scientific Center, Siberian Branch, Russian Academy of Sciences
- Edição: Volume 484, Nº 1 (2019)
- Páginas: 52-54
- Seção: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/212743
- DOI: https://doi.org/10.1134/S1607672919010150
- ID: 212743
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Resumo
To enhance the synthesis of antigenic envelope proteins L1 of high-grade papillomavirus types HPV16, HPV18, HPV31, and HPV45, the sequence of the gene encoding the cucumber mosaic virus replicase (RdRP CMV) was inserted into the genetic construct. This made it possible to increase the production of these antigenic proteins to 25–27 μg/mg total soluble protein.
Sobre autores
R. Salyaev
Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch, Russian Academy of Sciences
Autor responsável pela correspondência
Email: salyaev@sifibr.irk.ru
Rússia, Irkutsk, 664033
N. Rekoslavskaya
Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch, Russian Academy of Sciences; Irkutsk Scientific Center, Siberian Branch,Russian Academy of Sciences
Autor responsável pela correspondência
Email: rekoslavskaya@sifibr.irk.ru
Rússia, Irkutsk, 664033; Irkutsk, 664033
A. Stolbikov
Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch, Russian Academy of Sciences
Email: rekoslavskaya@sifibr.irk.ru
Rússia, Irkutsk, 664033
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