Stability of Chromatin Remodeling Complex Subunits Is Determined by Their Phosphorylation Status
- 作者: Azieva A.M.1,2, Sheinov A.A.1, Galkin F.A.1, Georgieva S.G.3, Soshnikova N.V.1
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隶属关系:
- Institute of Gene Biology
- Kurchatov Institute National Research Center
- Engelhardt Institute of Molecular Biology
- 期: 卷 479, 编号 1 (2018)
- 页面: 66-68
- 栏目: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/212140
- DOI: https://doi.org/10.1134/S1607672918020035
- ID: 212140
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详细
It was found that, in the differentiated cells of mouse brain, the level of core (Brg1 and BAF155) and specific (BRD7, BAF180, and PHF10) subunits of the chromatin-remodeling complex PBAF is reduced compared to the undifferentiated proliferating cells. Phosphorylation of PBAF complex subunits is required for maintaining their stability in differentiated brain cells.
作者简介
A. Azieva
Institute of Gene Biology; Kurchatov Institute National Research Center
Email: so2615nat@gmail.com
俄罗斯联邦, Moscow, 119334; Moscow, 123182
A. Sheinov
Institute of Gene Biology
Email: so2615nat@gmail.com
俄罗斯联邦, Moscow, 119334
F. Galkin
Institute of Gene Biology
Email: so2615nat@gmail.com
俄罗斯联邦, Moscow, 119334
S. Georgieva
Engelhardt Institute of Molecular Biology
Email: so2615nat@gmail.com
俄罗斯联邦, Moscow
N. Soshnikova
Institute of Gene Biology
编辑信件的主要联系方式.
Email: so2615nat@gmail.com
俄罗斯联邦, Moscow, 119334
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