Stability of Chromatin Remodeling Complex Subunits Is Determined by Their Phosphorylation Status
- Autores: Azieva A.M.1,2, Sheinov A.A.1, Galkin F.A.1, Georgieva S.G.3, Soshnikova N.V.1
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Afiliações:
- Institute of Gene Biology
- Kurchatov Institute National Research Center
- Engelhardt Institute of Molecular Biology
- Edição: Volume 479, Nº 1 (2018)
- Páginas: 66-68
- Seção: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/212140
- DOI: https://doi.org/10.1134/S1607672918020035
- ID: 212140
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Resumo
It was found that, in the differentiated cells of mouse brain, the level of core (Brg1 and BAF155) and specific (BRD7, BAF180, and PHF10) subunits of the chromatin-remodeling complex PBAF is reduced compared to the undifferentiated proliferating cells. Phosphorylation of PBAF complex subunits is required for maintaining their stability in differentiated brain cells.
Sobre autores
A. Azieva
Institute of Gene Biology; Kurchatov Institute National Research Center
Email: so2615nat@gmail.com
Rússia, Moscow, 119334; Moscow, 123182
A. Sheinov
Institute of Gene Biology
Email: so2615nat@gmail.com
Rússia, Moscow, 119334
F. Galkin
Institute of Gene Biology
Email: so2615nat@gmail.com
Rússia, Moscow, 119334
S. Georgieva
Engelhardt Institute of Molecular Biology
Email: so2615nat@gmail.com
Rússia, Moscow
N. Soshnikova
Institute of Gene Biology
Autor responsável pela correspondência
Email: so2615nat@gmail.com
Rússia, Moscow, 119334
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