Stability of Chromatin Remodeling Complex Subunits Is Determined by Their Phosphorylation Status


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Resumo

It was found that, in the differentiated cells of mouse brain, the level of core (Brg1 and BAF155) and specific (BRD7, BAF180, and PHF10) subunits of the chromatin-remodeling complex PBAF is reduced compared to the undifferentiated proliferating cells. Phosphorylation of PBAF complex subunits is required for maintaining their stability in differentiated brain cells.

Sobre autores

A. Azieva

Institute of Gene Biology; Kurchatov Institute National Research Center

Email: so2615nat@gmail.com
Rússia, Moscow, 119334; Moscow, 123182

A. Sheinov

Institute of Gene Biology

Email: so2615nat@gmail.com
Rússia, Moscow, 119334

F. Galkin

Institute of Gene Biology

Email: so2615nat@gmail.com
Rússia, Moscow, 119334

S. Georgieva

Engelhardt Institute of Molecular Biology

Email: so2615nat@gmail.com
Rússia, Moscow

N. Soshnikova

Institute of Gene Biology

Autor responsável pela correspondência
Email: so2615nat@gmail.com
Rússia, Moscow, 119334

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