Stability of Chromatin Remodeling Complex Subunits Is Determined by Their Phosphorylation Status
- Авторы: Azieva A.M.1,2, Sheinov A.A.1, Galkin F.A.1, Georgieva S.G.3, Soshnikova N.V.1
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Учреждения:
- Institute of Gene Biology
- Kurchatov Institute National Research Center
- Engelhardt Institute of Molecular Biology
- Выпуск: Том 479, № 1 (2018)
- Страницы: 66-68
- Раздел: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/212140
- DOI: https://doi.org/10.1134/S1607672918020035
- ID: 212140
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Аннотация
It was found that, in the differentiated cells of mouse brain, the level of core (Brg1 and BAF155) and specific (BRD7, BAF180, and PHF10) subunits of the chromatin-remodeling complex PBAF is reduced compared to the undifferentiated proliferating cells. Phosphorylation of PBAF complex subunits is required for maintaining their stability in differentiated brain cells.
Об авторах
A. Azieva
Institute of Gene Biology; Kurchatov Institute National Research Center
Email: so2615nat@gmail.com
Россия, Moscow, 119334; Moscow, 123182
A. Sheinov
Institute of Gene Biology
Email: so2615nat@gmail.com
Россия, Moscow, 119334
F. Galkin
Institute of Gene Biology
Email: so2615nat@gmail.com
Россия, Moscow, 119334
S. Georgieva
Engelhardt Institute of Molecular Biology
Email: so2615nat@gmail.com
Россия, Moscow
N. Soshnikova
Institute of Gene Biology
Автор, ответственный за переписку.
Email: so2615nat@gmail.com
Россия, Moscow, 119334
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