THE MODERN POSSIBILITIES OF DIAGNOSTICS, TREATMENT AND REHABILITATION OF PATIENTS WITH VARIANT FORMS OF AUTOIMMUNE DISEASES OF LIVER (PART II)

  • Authors: Burnevitch E.Z1, Arion E.A2, Aleksandrova E.A1
  • Affiliations:
    1. Первый Московский государственный медицинский университет им. И. М. Сеченова
    2. Клиника нефрологии, внутренних и профессиональных заболеваний им. Е. М. Тареева Первого Московского государственного медицинского университета им. И. М. Сеченова
  • Issue: Vol 15, No 1 (2012)
  • Pages: 42-45
  • Section: Articles
  • URL: https://journals.rcsi.science/1560-9537/article/view/35702
  • DOI: https://doi.org/10.17816/MSER35702
  • ID: 35702

Cite item

Full Text

Abstract

The patients with established autoimmune hepatitis having alkaline phosphatase or alkaline phosphatase/AST correlation increase more than 1,5 and whose conditions didn’t improve after immunosuppressor treatment should undergo ERCP or MRT cholangiography to identify the primary sclerosing cholangitis or AMA and to verify the possible primary biliary cirrhosis. On the other side, a range of patients with PBC and PSC had a high activity of hepatic processes that can be caused by combined autoimmune hepatitis. A combined therapy of immunosuppressor and ursodeoxycholic acid can impact the disease prognosis.

About the authors

E. Z Burnevitch

Первый Московский государственный медицинский университет им. И. М. Сеченова

Email: eduard.z.burnevich@mtu-net.ru
д-р мед. наук, проф. каф. терапии и профзаболеваний

E. A Arion

Клиника нефрологии, внутренних и профессиональных заболеваний им. Е. М. Тареева Первого Московского государственного медицинского университета им. И. М. Сеченова

врач отд-ния гепатологии

E. A Aleksandrova

Первый Московский государственный медицинский университет им. И. М. Сеченова

аспирант каф. терапии и профзаболеваний

References

  1. Alvarez F., Berg P. A., Bianchi F. B. et al. International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis // J. Hepatol. — 1999. — Vol. 31. — P. 929—938.
  2. Burak K. W., Urbanski S. J., Swain M. G. A case of coexisting primary biliary cirrhosis and primary sclerosing cholangitis: a new overlap of autoimmune liver diseases // Dig. Dis. Sci. — 2001. — Vol. 46. — P. 2043—2047.
  3. Chazouilleres O., Wendum D., Serfaty L. et al. Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome: clinical features and response to therapy // Hepatology. — 1998. — Vol. 28. — P. 296—301.
  4. Chazouilleres O., Wendum D., Serfaty L. et al. Long term outcome and response to therapy of primary biliary cirrhosis-autoimmune hepatitis overlap syndrome // J. Hepatol. — 2006. — Vol. 44. — P. 400—406.
  5. Colombato L. A., Alvarez F., Cote J., Huet P. M. Autoimmune cholangiopathy: the result of consecutive primary biliary cirrhosis and autoimmune hepatitis? // Gastroenterology. — 1994. — Vol. 107. — P. 1839—1843.
  6. Csepregi A., Rocken C., Treiber G., Malfertheiner P. Budesonide induces complete remission in autoimmune hepatitis // Wld J. Gastroenterol. — 2006. — Vol. 12. — P. 1362—1366.
  7. Czaja A. J. The variant forms of autoimmune hepatitis // Ann. Intern. Med. — 1996. — Vol. 125. — P. 588—598.
  8. Czaja A. J. Frequency and nature of the variant syndromes of autoimmune liver disease // Hepatology. — 1998. — Vol. 28. — P. 360—365.
  9. Duclos-Vallee J. C., Hadengue A., Ganne-Carrie N. et al. Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome. Corticoresistance and effective treatment by cyclosporine A // Dig. Dis. Sci. — 1995. — Vol. 40. — P. 1069—1073.
  10. Floreani A., Rizzotto E. R., Ferrara F. et al. Clinical course and outcome of autoimmune hepatitis/primary sclerosing cholangitis overlap syndrome // Am. J. Gastroenterol.— 2005. — Vol. 100. — P. 1516—1522.
  11. Gohlke F., Lohse A. W., Dienes H. P. et al. Evidence for an overlap syndrome of autoimmune hepatitis and primary sclerosing cholangitis // J. Hepatol. — 1996. — Vol. 24. — P. 699—705.
  12. Goodman Z. D., McNally P. R., Davis D. R., Ishak K. G. Autoimmune cholangitis: a variant of primary biliary cirrhosis. Clinicopathologic and serologic correlations in 200 cases // Dig. Dis. Sci. — 1995. — Vol. 40. — P. 1232—1242.
  13. Gregorio G. V., Portmann B., Karani J. et al. Autoimmune hepatitis/sclerosing cholangitis overlap syndrome in childhood: a 16-year prospective study // Hepatology. — 2001. — Vol. 33. — P. 544—553.
  14. Invernizzi P., Selmi C., Ranftler C. et al. Antinuclear antibodies in primary biliary cirrhosis // Semin. Liver Dis. — 2005. — Vol. 25. — P. 298—310.
  15. Joshi S., Cauch-Dudek K., Wanless I. R. et al. Primary biliary cirrhosis with additional features of autoimmune hepatitis: response to therapy with ursodeoxycholic acid // Hepatology. — 2002. — Vol. 35. — P. 409—413.
  16. Kanzler S., Bozkurt S., Herkel J. et al. Nachweis von SLA/LPAutoantikorpern bei Patienten mit primar biliarer Zirrhose als Marker für eine sekundare autoimmune Hepatitis (Overlapsyn-drom) // Dtsch. Med. Wschr. — 2001. — Bd 126. — S. 450—456.
  17. Kaya M., Angulo P., Lindor K. D. Overlap of autoimmune hepatitis and primary sclerosing cholangitis: an evaluation of a modified scoring system // J. Hepatol. — 2000. — Vol. 33. — P. 537—542.
  18. Kloppel G., Seifert G., Lindner H. et al. Histopathological features in mixed types of chronic aggressive hepatitis and primary biliary cirrhosis. Correlations of liver histology with mitochondrial antibodies of different specificity // Virch. Arch. Pathol. Anat. Histol. — 1977. — Bd 373 — S. 143—160.
  19. Krams S. M., Van de Water J., Coppel R. L. et al. Analysis of hepatic T-lymphocyte and immunoglobulin deposits in patients with primary biliary cirrhosis // Hepatology. — 1990. — Vol. 12. — P. 306—313.
  20. Li C. P., Tong M. J., Hwang S. J. et al. Autoimmune cholangitis with features of autoimmune hepatitis: successful treatment with immunosuppressive agents and ursodeoxycholic acid // J. Gastroenterol. Hepatol. — 2000. — Vol. 15. — P. 95—98.
  21. Lindor K. D. Ursodiol for primary sclerosing cholangitis. Mayo Primary Sclerosing Cholangitis-Ursodeoxycholic Acid Study Group // N. Engl. J. Med. — 1997. — Vol. 336. — P. 691—695.
  22. Lohse A. W., zum Buschenfelde K. H., Franz B. et al. Characterization of the overlap syndrome of primary biliary cirrhosis and autoimmune hepatitis: evidence for it being a hepatitic form of PBC in genetically susceptible individuals // Hepatology. — 1999. — Vol. 29. — P. 1078—1084.
  23. Michieletti P., Wanless I. R., Katz A. et al. Antimitochondrial antibody negative primary biliary cirrhosis: a distinct syndrome of autoimmune cholangitis // Gut. — 1994. — Vol. 35. — P. 260—265.
  24. Minak G., Sutherland L. R., Pappas C. et al. Autoimmune chronic active hepatitis (lupoid hepatitis) and primary sclerosing cholangitis in two young adult females // Can. J. Gastroenterol. — 1988. — Vol. 2. — P. 22—27.
  25. Mitchell S. A., Bansi D. S., Hunt N. et al. A preliminary trial of high-dose ursodeoxycholic acid in primary sclerosing cholangitis // Gastroenterology. — 2001. — Vol. 121. — P. 900—907.
  26. Rust C., Beuers U. Medical treatment of primary biliary cirrhosis and primary sclerosing cholangitis // Clin. Rev. Allergy Immunol. — 2005. — Vol. 28. — P. 135—145.
  27. Silveira M. G., Talwalkar J. A., Angulo P., Lindor K. D. Overlap of autoimmune hepatitis and primary biliary cirrhosis: longterm outcomes // Am. J. Gastroenterol. — 2007. — Vol. 102. — P. 1244—1250.
  28. Terjung B., Spengler U. Role of auto-antibodies for the diagnosis of chronic cholestatic liver diseases // Clin. Rev. Allergy Immunol. — 2005. — Vol. 28. — P. 115—133.
  29. Wurbs D., Klein R., Terracciano L. M. et al. A 28-year-old woman with a combined hepatitic/cholestatic syndrome (clinical conference) // Hepatology. — 1995. — Vol. 22. — P. 1598—1605.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2012 Eco-Vector



Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).