Email this article Halocyclization of 2-allyl(propargyl)sulfanyl-6-aminopyrimidin-4(3H)-ones
- Authors: Kim D.G.1, Osheko K.Y.1, Frolova T.V.1
-
Affiliations:
- South Ural State University
- Issue: Vol 53, No 12 (2017)
- Pages: 1899-1902
- Section: Short Communications
- URL: https://journals.rcsi.science/1070-4280/article/view/217096
- DOI: https://doi.org/10.1134/S1070428017120235
- ID: 217096
Cite item
Open Access
Access granted
Subscription Access
Abstract
The alkylation of 6-amino-2-thiouracil with allyl, methallyl, and propargyl halides in the presence of bases gave 2-[allyl(methallyl, propargyl)sulfanyl]-6-aminopyrimidin-4(3H)-ones which reacted with iodine and bromine to form fused [1,3]thiazolo[3,2-a]pyrimidinium systems. Their nitrosation with sodium nitrite in acid medium afforded 2-[allyl(propargyl)sulfanyl]-6-amino-5-nitrosopyrimidin-4(3H)-ones.
About the authors
D. G. Kim
South Ural State University
Author for correspondence.
Email: kim_dg48@mail.ru
Russian Federation, pr. imeni Lenina 76, Chelyabinsk, 454080
K. Yu. Osheko
South Ural State University
Email: kim_dg48@mail.ru
Russian Federation, pr. imeni Lenina 76, Chelyabinsk, 454080
T. V. Frolova
South Ural State University
Email: kim_dg48@mail.ru
Russian Federation, pr. imeni Lenina 76, Chelyabinsk, 454080
Supplementary files
