电邮这篇文章 Synthesis of Macrocyclic Ttipeptidopyridine Schiff Base Candidates
- 作者: Sallam H.1, Abdel-Mageid R.2, Amr A.3,4
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隶属关系:
- Synthetic Organic Lab, Chemistry Department, Faculty of Science
- Department of Photochemistry
- Pharmaceutical Chemistry Department, College of Pharmacy, Drug Exploration and Development Chair (DEDC)
- Applied Organic Chemistry Department
- 期: 卷 89, 编号 11 (2019)
- 页面: 2308-2313
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223177
- DOI: https://doi.org/10.1134/S1070363219110239
- ID: 223177
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详细
In the current study, a series of macrocyclic tripeptide Schiff bases 2–6 were synthesized by using macrocyclic tripeptide hydrazide 1 as starting material. Treatment of hydrazide 1 with active carbonyl cycloalkanones gave cycloalkanone hydrazines 2a–2d. Also, condensation of 1 with aromatic and heterocyclic aldehydes, or aromatic and heterocyclic acetyl derivatives afforded the corresponding Schiff base candidates 3a–3e, 4a–4c, 5a–5c, and 6a–6c, respectively.
作者简介
H. Sallam
Synthetic Organic Lab, Chemistry Department, Faculty of Science
Email: aamr@ksu.edu.sa
埃及, Abbassia, Cairo, 11566
R. Abdel-Mageid
Department of Photochemistry
Email: aamr@ksu.edu.sa
埃及, Dokki, Cairo, 12622
A. Amr
Pharmaceutical Chemistry Department, College of Pharmacy, Drug Exploration and Development Chair (DEDC); Applied Organic Chemistry Department
编辑信件的主要联系方式.
Email: aamr@ksu.edu.sa
沙特阿拉伯, Riyadh, 11451; Dokki, Cairo, 12622
