Мақаланы E-mail арқылы жіберу Synthesis of Macrocyclic Ttipeptidopyridine Schiff Base Candidates
- Авторлар: Sallam H.1, Abdel-Mageid R.2, Amr A.3,4
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Мекемелер:
- Synthetic Organic Lab, Chemistry Department, Faculty of Science
- Department of Photochemistry
- Pharmaceutical Chemistry Department, College of Pharmacy, Drug Exploration and Development Chair (DEDC)
- Applied Organic Chemistry Department
- Шығарылым: Том 89, № 11 (2019)
- Беттер: 2308-2313
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223177
- DOI: https://doi.org/10.1134/S1070363219110239
- ID: 223177
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Аннотация
In the current study, a series of macrocyclic tripeptide Schiff bases 2–6 were synthesized by using macrocyclic tripeptide hydrazide 1 as starting material. Treatment of hydrazide 1 with active carbonyl cycloalkanones gave cycloalkanone hydrazines 2a–2d. Also, condensation of 1 with aromatic and heterocyclic aldehydes, or aromatic and heterocyclic acetyl derivatives afforded the corresponding Schiff base candidates 3a–3e, 4a–4c, 5a–5c, and 6a–6c, respectively.
Негізгі сөздер
Авторлар туралы
H. Sallam
Synthetic Organic Lab, Chemistry Department, Faculty of Science
Email: aamr@ksu.edu.sa
Египет, Abbassia, Cairo, 11566
R. Abdel-Mageid
Department of Photochemistry
Email: aamr@ksu.edu.sa
Египет, Dokki, Cairo, 12622
A. Amr
Pharmaceutical Chemistry Department, College of Pharmacy, Drug Exploration and Development Chair (DEDC); Applied Organic Chemistry Department
Хат алмасуға жауапты Автор.
Email: aamr@ksu.edu.sa
Сауд Арабиясы, Riyadh, 11451; Dokki, Cairo, 12622
