Synthesis and Properties of 4,6-Dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile and 3-Amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines
- 作者: Buryi D.1, Dotsenko V.1,2,3, Aksenov N.2, Aksenova I.2, Krivokolysko S.3,4, Dyadyuchenko L.5
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隶属关系:
- Kuban State University
- North Caucasus Federal University
- KhimEks Laboratory
- St. Luka Lugansk State Medical University
- All-Russian Research Institute of Biological Plant Protection
- 期: 卷 89, 编号 8 (2019)
- 页面: 1575-1585
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223021
- DOI: https://doi.org/10.1134/S1070363219080061
- ID: 223021
如何引用文章
详细
The reaction of 3-pentylpentane-2,4-dione with cyanothioacetamide afforded 4,6-dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile. Alkylation of the latter led to the formation of 2-alkylsulfanyl-4,6-dimethyl-5-pentylpyridine-3-carbonitriles or 3-amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines, depending on the alkylating agent and reaction conditions. The structures of the key compounds were proved by 2D NMR spectroscopy and X-ray analysis. Biological activity of the synthesized compounds was evaluated in silico. Some compounds were experimentally found to stimulate growth of sunflower seedlings.
作者简介
D. Buryi
Kuban State University
编辑信件的主要联系方式.
Email: victor_dotsenko_@mail.ru
俄罗斯联邦, Krasnodar
V. Dotsenko
Kuban State University; North Caucasus Federal University; KhimEks Laboratory
Email: victor_dotsenko_@mail.ru
俄罗斯联邦, Krasnodar; Stavropol; Lugansk
N. Aksenov
North Caucasus Federal University
Email: victor_dotsenko_@mail.ru
俄罗斯联邦, Stavropol
I. Aksenova
North Caucasus Federal University
Email: victor_dotsenko_@mail.ru
俄罗斯联邦, Stavropol
S. Krivokolysko
KhimEks Laboratory; St. Luka Lugansk State Medical University
Email: victor_dotsenko_@mail.ru
乌克兰, Lugansk; Lugansk
L. Dyadyuchenko
All-Russian Research Institute of Biological Plant Protection
Email: victor_dotsenko_@mail.ru
俄罗斯联邦, Krasnodar
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