5-Amino-Substituted Derivatives of 4-Nitrofurazane: Synthesis, Structure, and Biological Activity
- 作者: Galkina I.1, Takhautdinova G.1, Ivshin K.1, Khayarov K.1, Islamov D.1, Bakhtiyarova Y.1, Yamalieva L.1, Kataeva O.1, Galkin V.1
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隶属关系:
- Kazan (Volga Region) Federal University, ul. Kremlevskaya 18
- 期: 卷 88, 编号 5 (2018)
- 页面: 898-902
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222177
- DOI: https://doi.org/10.1134/S1070363218050092
- ID: 222177
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详细
New amination reactions of 5-chloro-4-nitrobenzofurazane with different amines were studied. The reactions of 5-chloro-4-nitrobenzofurazane with 2,4,6-trichloro-, para-acetyl-, and para-carboxyethylanilines gave the products of aromatic nucleophilic substitution of the chlorine substituent in the nitrogenous heterocycle, the composition and structure of which was established by chemical, physical, and physicochemical methods and X-ray diffraction analysis. The thermal stability was studied by synchronous thermogravimetry and differential scanning calorimetry (TG‒DSC). The synthesized compounds showed a high antibacterial and antimycotic activity against human and animal pathogenic microflora.
作者简介
I. Galkina
Kazan (Volga Region) Federal University, ul. Kremlevskaya 18
编辑信件的主要联系方式.
Email: vig54@mail.ru
俄罗斯联邦, Kazan, Tatarstan, 420008
G. Takhautdinova
Kazan (Volga Region) Federal University, ul. Kremlevskaya 18
Email: vig54@mail.ru
俄罗斯联邦, Kazan, Tatarstan, 420008
K. Ivshin
Kazan (Volga Region) Federal University, ul. Kremlevskaya 18
Email: vig54@mail.ru
俄罗斯联邦, Kazan, Tatarstan, 420008
Kh. Khayarov
Kazan (Volga Region) Federal University, ul. Kremlevskaya 18
Email: vig54@mail.ru
俄罗斯联邦, Kazan, Tatarstan, 420008
D. Islamov
Kazan (Volga Region) Federal University, ul. Kremlevskaya 18
Email: vig54@mail.ru
俄罗斯联邦, Kazan, Tatarstan, 420008
Yu. Bakhtiyarova
Kazan (Volga Region) Federal University, ul. Kremlevskaya 18
Email: vig54@mail.ru
俄罗斯联邦, Kazan, Tatarstan, 420008
L. Yamalieva
Kazan (Volga Region) Federal University, ul. Kremlevskaya 18
Email: vig54@mail.ru
俄罗斯联邦, Kazan, Tatarstan, 420008
O. Kataeva
Kazan (Volga Region) Federal University, ul. Kremlevskaya 18
Email: vig54@mail.ru
俄罗斯联邦, Kazan, Tatarstan, 420008
V. Galkin
Kazan (Volga Region) Federal University, ul. Kremlevskaya 18
Email: vig54@mail.ru
俄罗斯联邦, Kazan, Tatarstan, 420008