Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-6-(substituted phenyl)-1,2-dihydro-2-oxo(imino)pyridine-3-carbonitriles


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详细

A novel compounds of 4,6-diaryl-2-oxo(imino)-1,2-dihydro-pyridine-3-carbonitriles has been synthesized by reaction of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different 1-(substituted phenyl)ethanones and ethyl cyanoacetate or malononitrile in presence of ammonium acetate. Structure of the newly synthesized compounds was elucidated from chemical and spectroscopic data.

作者简介

N. Khalifa

Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of Pharmacy; Therapeutical Chemistry Department, Pharmaceutical and Drug Industries Division

编辑信件的主要联系方式.
Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451; Dokki, Cairo, 12622

M. Al-Omar

Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of Pharmacy

Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451

O. Ali

Department of Chemistry, Faculty of Medical and Applied Science

Email: nagykhalifa@hotmail.com
沙特阿拉伯, Taif


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