Enviar artigo por via de e-mail Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-6-(substituted phenyl)-1,2-dihydro-2-oxo(imino)pyridine-3-carbonitriles
- Autores: Khalifa N.1,2, Al-Omar M.1, Ali O.3
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Afiliações:
- Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of Pharmacy
- Therapeutical Chemistry Department, Pharmaceutical and Drug Industries Division
- Department of Chemistry, Faculty of Medical and Applied Science
- Edição: Volume 87, Nº 12 (2017)
- Páginas: 2933-2936
- Seção: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/221768
- DOI: https://doi.org/10.1134/S1070363217120349
- ID: 221768
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Resumo
A novel compounds of 4,6-diaryl-2-oxo(imino)-1,2-dihydro-pyridine-3-carbonitriles has been synthesized by reaction of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different 1-(substituted phenyl)ethanones and ethyl cyanoacetate or malononitrile in presence of ammonium acetate. Structure of the newly synthesized compounds was elucidated from chemical and spectroscopic data.
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Sobre autores
N. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of Pharmacy; Therapeutical Chemistry Department, Pharmaceutical and Drug Industries Division
Autor responsável pela correspondência
Email: nagykhalifa@hotmail.com
Arábia Saudita, Riyadh, 11451; Dokki, Cairo, 12622
M. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair, College of Pharmacy
Email: nagykhalifa@hotmail.com
Arábia Saudita, Riyadh, 11451
O. Ali
Department of Chemistry, Faculty of Medical and Applied Science
Email: nagykhalifa@hotmail.com
Arábia Saudita, Taif
