Synthesis, spectral characterization, DNA interaction, antioxidant, and antimicrobial studies of new water soluble metal(II) complexes of morpholine based ligand
- 作者: Vedhi C.1, Dhaveethu Raja J.2, Senthilkumar G.2,3, Sankarganesh M.2, Rajesh J.2
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隶属关系:
- PG and Research Department of Chemistry
- Chemistry Research Centre
- Department of Chemistry Manonmaniam Sundaranar University
- 期: 卷 87, 编号 11 (2017)
- 页面: 2654-2663
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221607
- DOI: https://doi.org/10.1134/S1070363217110214
- ID: 221607
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详细
A new series of metal(II) complexes 1–5 of the type [M(L)(AcO)2H2O], where L is a bidentate ligand, 2-(3-morpholinopropylimino)methylphenol and M is Mn(II) (1), Co(II) (2), Ni(II) (3), Cu(II) (4), and Zn(II) (5), have been isolated and characterized by physico-chemical and spectral methods. Spectroscopic data supported the square pyramidal geometry around the central metal ion in the complexes 1–5. Absorption spectra and viscometric data indicated that the complexes 1–5 interacted with calf thymus (CT) DNA via intercalative strategy. Cleavage activities of complexes 1–5 with CT DNA were analyzed by gelelectrophoretic method. The in vitro antioxidant activity of complexes 1–5 was tested using the DPPH assay. The complexes 1–5 have been tested for antimicrobial activity against some pathogenic bacterial and fungal species by the agar well diffusion method.
作者简介
C. Vedhi
PG and Research Department of Chemistry
Email: jdrajapriya@gmail.com
印度, Thoothukudi, Tamil Nadu, 628008
J. Dhaveethu Raja
Chemistry Research Centre
编辑信件的主要联系方式.
Email: jdrajapriya@gmail.com
印度, Kilakarai, Ramanathapuram, Tamil Nadu, 623806
G. Senthilkumar
Chemistry Research Centre; Department of Chemistry Manonmaniam Sundaranar University
Email: jdrajapriya@gmail.com
印度, Kilakarai, Ramanathapuram, Tamil Nadu, 623806; Tirunelveli, Tamil Nadu, 627012
M. Sankarganesh
Chemistry Research Centre
Email: jdrajapriya@gmail.com
印度, Kilakarai, Ramanathapuram, Tamil Nadu, 623806
J. Rajesh
Chemistry Research Centre
Email: jdrajapriya@gmail.com
印度, Kilakarai, Ramanathapuram, Tamil Nadu, 623806
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