Synthesis, structure, and antimicrobial activity of methyl (4-alkanoyl-3-hydroxy-1,5-diaryl-1 H -pyrrol-2-yl)acetates

P. P. Mukovoz; P. A. Slepukhin; O. S. El’tsov; I. N. Ganebnykh; A. V. Gorbunova; A. N. Sizentsov; M. L. Rusyaeva

doi:10.1134/S1070363217100085

Synthesis, structure, and antimicrobial activity of methyl (4-alkanoyl-3-hydroxy-1,5-diaryl-1H-pyrrol-2-yl)acetates

作者: Mukovoz P.¹, Slepukhin P.²^,3, El’tsov O.³, Ganebnykh I.²^,3, Gorbunova A.⁴, Sizentsov A.⁴, Rusyaeva M.⁴
隶属关系:
1. Moscow Institute of Technology (Orenburg Branch)
2. Postovskii Institute of Organic Synthesis
3. Yeltsin Ural Federal University
4. Orenburg State University
期: 卷 87, 编号 10 (2017)
页面: 2291-2298
栏目: Article
URL: https://journals.rcsi.science/1070-3632/article/view/221401
DOI: https://doi.org/10.1134/S1070363217100085
ID: 221401

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详细

Reactions of methyl 3,4,6-trioxoalkanoates (3,4-dihydroxy-6-oxo-2,4-alkadienoates) with a mixture of arylamines and aromatic aldehydes or with the corresponding arylidenearylamines lead to the formation of methyl (4- alkanoyl-3-hydroxy-1,5-diaryl-1H-pyrrol-2-yl)acetates. Structure of the synthesized compounds is discussed basing on IR, ¹H NMR spectroscopy, mass spectrometry, and X-ray diffraction data.