Synthesis, structure, and antimicrobial activity of methyl (4-alkanoyl-3-hydroxy-1,5-diaryl-1H-pyrrol-2-yl)acetates
- Authors: Mukovoz P.P.1, Slepukhin P.A.2,3, El’tsov O.S.3, Ganebnykh I.N.2,3, Gorbunova A.V.4, Sizentsov A.N.4, Rusyaeva M.L.4
-
Affiliations:
- Moscow Institute of Technology (Orenburg Branch)
- Postovskii Institute of Organic Synthesis
- Yeltsin Ural Federal University
- Orenburg State University
- Issue: Vol 87, No 10 (2017)
- Pages: 2291-2298
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221401
- DOI: https://doi.org/10.1134/S1070363217100085
- ID: 221401
Cite item
Abstract
Reactions of methyl 3,4,6-trioxoalkanoates (3,4-dihydroxy-6-oxo-2,4-alkadienoates) with a mixture of arylamines and aromatic aldehydes or with the corresponding arylidenearylamines lead to the formation of methyl (4- alkanoyl-3-hydroxy-1,5-diaryl-1H-pyrrol-2-yl)acetates. Structure of the synthesized compounds is discussed basing on IR, 1H NMR spectroscopy, mass spectrometry, and X-ray diffraction data.
About the authors
P. P. Mukovoz
Moscow Institute of Technology (Orenburg Branch)
Author for correspondence.
Email: mpp27@mail.ru
Russian Federation, pr. Pobedy 75, Orenburg, 460018
P. A. Slepukhin
Postovskii Institute of Organic Synthesis; Yeltsin Ural Federal University
Email: mpp27@mail.ru
Russian Federation, Yekaterinburg; Yekaterinburg
O. S. El’tsov
Yeltsin Ural Federal University
Email: mpp27@mail.ru
Russian Federation, Yekaterinburg
I. N. Ganebnykh
Postovskii Institute of Organic Synthesis; Yeltsin Ural Federal University
Email: mpp27@mail.ru
Russian Federation, Yekaterinburg; Yekaterinburg
A. V. Gorbunova
Orenburg State University
Email: mpp27@mail.ru
Russian Federation, Orenburg
A. N. Sizentsov
Orenburg State University
Email: mpp27@mail.ru
Russian Federation, Orenburg
M. L. Rusyaeva
Orenburg State University
Email: mpp27@mail.ru
Russian Federation, Orenburg