电邮这篇文章 Functionalization of 5-(4-alkoxybenzyl)-4-R-4H-1,2,4-triazole-3-thiols. Synthesis of novel DNA methylation inhibitors
- 作者: Hakobyan M.1, Hovsepyan T.1, Nersesyan L.1, Agaronyan A.1, Danielyan I.1, Paronikyan R.1, Minasyan N.2
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隶属关系:
- A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
- Molecular Structure Research Center, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
- 期: 卷 87, 编号 5 (2017)
- 页面: 973-978
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/219740
- DOI: https://doi.org/10.1134/S1070363217050140
- ID: 219740
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详细
Aminomethylation and cyanoethylation reactions of 5-(4-alkoxybenzyl)-4-methyl(phenyl, allyl)-4H-1,2,4-triazole-3-thiols have been investigated. According to NMR spectroscopy data, the reactions occur at the nitrogen atom Ν2. The effect of the synthesized compounds on cancer DNA methylation has been evaluated.
作者简介
M. Hakobyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
亚美尼亚, pr. Azatutyan 26, Yerevan, 0014
T. Hovsepyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
编辑信件的主要联系方式.
Email: tag.hovsepyan@mail.ru
亚美尼亚, pr. Azatutyan 26, Yerevan, 0014
L. Nersesyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
亚美尼亚, pr. Azatutyan 26, Yerevan, 0014
A. Agaronyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
亚美尼亚, pr. Azatutyan 26, Yerevan, 0014
I. Danielyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
亚美尼亚, pr. Azatutyan 26, Yerevan, 0014
R. Paronikyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
亚美尼亚, pr. Azatutyan 26, Yerevan, 0014
N. Minasyan
Molecular Structure Research Center, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
亚美尼亚, Yerevan
