Мақаланы E-mail арқылы жіберу Functionalization of 5-(4-alkoxybenzyl)-4-R-4H-1,2,4-triazole-3-thiols. Synthesis of novel DNA methylation inhibitors
- Авторлар: Hakobyan M.1, Hovsepyan T.1, Nersesyan L.1, Agaronyan A.1, Danielyan I.1, Paronikyan R.1, Minasyan N.2
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Мекемелер:
- A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
- Molecular Structure Research Center, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
- Шығарылым: Том 87, № 5 (2017)
- Беттер: 973-978
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/219740
- DOI: https://doi.org/10.1134/S1070363217050140
- ID: 219740
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
Aminomethylation and cyanoethylation reactions of 5-(4-alkoxybenzyl)-4-methyl(phenyl, allyl)-4H-1,2,4-triazole-3-thiols have been investigated. According to NMR spectroscopy data, the reactions occur at the nitrogen atom Ν2. The effect of the synthesized compounds on cancer DNA methylation has been evaluated.
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Авторлар туралы
M. Hakobyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014
T. Hovsepyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Хат алмасуға жауапты Автор.
Email: tag.hovsepyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014
L. Nersesyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014
A. Agaronyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014
I. Danielyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014
R. Paronikyan
A.L. Mnjoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
Армения, pr. Azatutyan 26, Yerevan, 0014
N. Minasyan
Molecular Structure Research Center, Scientific-Technological Center of Organic and Pharmaceutical Chemistry
Email: tag.hovsepyan@mail.ru
Армения, Yerevan
