Synthesis and characterization of some novel 1,3-diaryl pyrazole bearing 2-oxopyridine-3,5-dicarbonitrile derivatives


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详细

A series of new 1-{[1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methyleneamino}-6-amino-1,2-dihydro-4-(substitutedphenyl)-2-oxopyridine-3,5-di carbonitrile derivatives (4a–4i) were synthesized and characterized via cyclization of the key intermediate (E)-N'-([1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methylene}-2-cyanoaceto hydrazide with different 2-arylidenemalononitrile.

作者简介

N. Khalifa

Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division

编辑信件的主要联系方式.
Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451; Dokki, Cairo, 12622

M. Al-Omar

Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy

Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451

E. Nossier

Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)

Email: nagykhalifa@hotmail.com
埃及, Cairo, 11754


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