Отправить статью по E-mail Synthesis and characterization of some novel 1,3-diaryl pyrazole bearing 2-oxopyridine-3,5-dicarbonitrile derivatives
- Авторы: Khalifa N.1,2, Al-Omar M.1, Nossier E.3
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Учреждения:
- Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
- Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
- Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
- Выпуск: Том 87, № 4 (2017)
- Страницы: 846-849
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/219465
- DOI: https://doi.org/10.1134/S1070363217040296
- ID: 219465
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Аннотация
A series of new 1-{[1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methyleneamino}-6-amino-1,2-dihydro-4-(substitutedphenyl)-2-oxopyridine-3,5-di carbonitrile derivatives (4a–4i) were synthesized and characterized via cyclization of the key intermediate (E)-N'-([1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methylene}-2-cyanoaceto hydrazide with different 2-arylidenemalononitrile.
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Об авторах
N. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
Автор, ответственный за переписку.
Email: nagykhalifa@hotmail.com
Саудовская Аравия, Riyadh, 11451; Dokki, Cairo, 12622
M. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Саудовская Аравия, Riyadh, 11451
E. Nossier
Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
Email: nagykhalifa@hotmail.com
Египет, Cairo, 11754
