Design and development of macrocyclization methods for compounds with potential tuberculocidal activity to decrease CYP450 liver cytochrome inhibition
- 作者: Vasilevich N.1, Aksenova E.1, Aksenova A.1, Afanasyev I.1
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隶属关系:
- New Scientific Technologies
- 期: 卷 87, 编号 4 (2017)
- 页面: 717-730
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/219195
- DOI: https://doi.org/10.1134/S1070363217040107
- ID: 219195
如何引用文章
详细
A procedure for macrocyclization of compounds with potential tuberculocidal activity was developed in order to obtaining compounds with a lower degree of inhibition of the key CYP 3A4 cytochrome.
作者简介
N. Vasilevich
New Scientific Technologies
编辑信件的主要联系方式.
Email: nvasilevich@asinex.com
俄罗斯联邦, ul. Geroev Panfilovtsev 20, Moscow, 125480
E. Aksenova
New Scientific Technologies
Email: nvasilevich@asinex.com
俄罗斯联邦, ul. Geroev Panfilovtsev 20, Moscow, 125480
A. Aksenova
New Scientific Technologies
Email: nvasilevich@asinex.com
俄罗斯联邦, ul. Geroev Panfilovtsev 20, Moscow, 125480
I. Afanasyev
New Scientific Technologies
Email: nvasilevich@asinex.com
俄罗斯联邦, ul. Geroev Panfilovtsev 20, Moscow, 125480